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Image Search Results
Journal: PLoS ONE
Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders
doi: 10.1371/journal.pone.0240517
Figure Lengend Snippet: Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, PT1, C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Article Snippet: Cells were treated with either DMSO or
Techniques: Control, Fluorescence
Journal: PLoS ONE
Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders
doi: 10.1371/journal.pone.0240517
Figure Lengend Snippet: Mitochondrial-deficient patient fibroblasts were treated with the AMPK agonist PT1 or DMSO (vehicle) and morphology was visualized by phase contrast microscopy. Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG.
Article Snippet: Cells were treated with either DMSO or
Techniques: Microscopy
Journal: PLoS ONE
Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders
doi: 10.1371/journal.pone.0240517
Figure Lengend Snippet: COX10-deficient patient fibroblasts were transfected with AMPK-specific siRNA (siAMPK) or control siRNA (siCNT). Following transfection, cells were ( A ) evaluated for protein expression by western blotting, or ( B ) treated with PT1 or DMSO (vehicle) for an additional 6 days and then evaluated for viability by calcein-AM fluorescence assay and ( C ) morphology by phase contrast microscopy.
Article Snippet: Cells were treated with either DMSO or
Techniques: Transfection, Control, Expressing, Western Blot, Fluorescence, Microscopy
Journal: Frontiers in Bioengineering and Biotechnology
Article Title: Predicting shock-induced cavitation using machine learning: implications for blast-injury models
doi: 10.3389/fbioe.2024.1268314
Figure Lengend Snippet: Pressure–time traces from pressure transducers PT0 and PT1, located on the driven section of the shock tube.
Article Snippet: Piezoelectric pressure transducers 0 and 1 (PT0 and
Techniques: