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Image Search Results
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Regional distribution of molecules related with Aβ metabolism. After normalization within each individual, levels of apoE in TBS fraction (a) and in TBS-TX fraction (b), APP (c), APP-CTFβ (d), BACE1 (e), presenilin-1 (f), NEP (g), IDE (h), LRP1 (i), LDLR (j), synaptophysin (k), PSD95 (l), lactate (m), and GFAP (n) are plotted by different brain areas with the average line of each area. The p < 0.05 was considered significant; paired t test with Holm correction for multiple comparisons. PS1 presenilin-1, SYP synaptophysin
Article Snippet: The recombinant
Techniques:
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Regional associations between Aβ in each fraction and molecules related to Aβ metabolism
Article Snippet: The recombinant
Techniques:
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Strong regional associations between Aβ and PSD95 or apoE. a PSD95 levels in each brain area are plotted against Aβ40 levels in TBS fraction in each brain area. b ApoE levels in TBS-TX fraction in each brain area are plotted against Aβ40 levels in TBS-TX fraction in each brain area. c ApoE levels in TBS fraction in each brain area are plotted against Aβ40 levels in GuHCl fraction in each brain area. Values are median with 25 and 75 percentiles. Correlation coefficient (r) and p value were acquired by Spearman rank correlation test. GuH GuHCl
Article Snippet: The recombinant
Techniques:
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Regional associations among molecules related to Aβ metabolism
Article Snippet: The recombinant
Techniques:
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Strong regional associations among molecules related to Aβ metabolism. a GFAP levels in each brain area are plotted against apoE levels in TBS fraction in each brain area. b PSD95 levels in each brain area are plotted against LRP1 levels in each brain area. c GFAP levels in each brain area are plotted against lactate levels in each brain area. Values are median with 25 and 75 percentiles. Correlation coefficient (r) and p value were acquired by Spearman rank correlation test
Article Snippet: The recombinant
Techniques:
Journal: Acta neuropathologica
Article Title: Brain regional correlation of amyloid-? with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-? accumulation
doi: 10.1007/s00401-013-1086-9
Figure Lengend Snippet: Correlation map based on the regional associations between Aβ and molecules related with Aβ metabolism. a Correlation map are depicted based on the regional associations among Aβ40 in TBS fraction, apoE in TBS fraction, GFAP, PSD95, and LRP1. b Correlation map are depicted based on the regional associations among Aβ40 in TBS-TX and GuHCl fraction, apoE in TBS fraction, GFAP,PSD95, and LRP1. Values indicate correlation coefficient (r). Red line indicates a positive association. Blue line indicates a negative association. Solid line indicates statistical significant associations observed between two molecules. Dashed line indicates no statistical significant associations between two molecules. Bold line indicates the strongest correlation between Aβ40 and PSD95, and between Aβ40 and apoE
Article Snippet: The recombinant
Techniques: