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Image Search Results
Journal: Chinese Medicine
Article Title: Dendrobine alleviates CCl 4 -induced acute liver injury by inhibiting necroptosis through activation of the Nrf2/PPARγ/SOD2 signaling pathways
doi: 10.1186/s13020-025-01241-8
Figure Lengend Snippet: DDB binds to the Kelch structural domain of Keap1. A The DDB binding sequence was located within the Kelch domain of Keap1. B The interaction between DDB and Keap1 was explored by means of the CETSA assay (n = 3). C Western blot analysis showed that DDB enhanced the resistance of Keap1 to proenzyme digestion in AML-12 cells (n = 3). Compared with the control group, ** P < 0.01; compared with the pronase group, # P < 0.05
Article Snippet: The lysate was divided into four aliquots, which were each treated with DMSO or DDB (1 μM) at RT for 1 h. Post-incubation, the samples were further treated with
Techniques: Binding Assay, Sequencing, Western Blot, Control