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NSJ Bioreagents
ppp2ca antibody / pp2a alpha Ppp2ca Antibody / Pp2a Alpha, supplied by NSJ Bioreagents, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/ppp2ca+antibody/PPP2CA+Antibody+%2F+PP2A+alpha/custom%40rq5853%4028947679 Average 99 stars, based on 1 article reviews
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Proteintech
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OriGene
ppp2ca ![]() Ppp2ca, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/ppp2ca+antibody/PP2A-alpha+(PPP2CA)+Goat+Polyclonal+Antibody/pm21806946-23-39-42 Average 90 stars, based on 1 article reviews
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Atlas Antibodies
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Merck KGaA
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Cusabio
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Aviva Systems
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PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By
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Image Search Results
Journal: Gastroenterology
Article Title: Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors.
doi: 10.1053/j.gastro.2011.07.038
Figure Lengend Snippet: Figure 5. NT activates AKT through suppression of PPP2CA by direct interaction with miR-155. (A) miR-155 binding sites in 3=UTRs of PPP2CA predicted by Lever algorithm analysis. (B) Luciferase activity of the PPP2CA 3=UTRs in HCT116 and DLD1 cells transfected with as-miR-155 (100 nmol/L) or as-miR-155 (100 nmol/L) for 24 hours. (C) Luciferase activity of the PPP2CA 3=UTRs in HCT116 and DLD1 cells treated with NT (100 nmol/L). (D) PPP2CA and -actin protein levels, assessed by Western blot, in NT-treated (100 nmol/L, 6 h) HCT116 and DLD1 cells. (E) AKT phosphorylation (S473) levels, assessed by enzyme-linked immunosorbent assay, in HCT116 and DLD1 cells transfected with miR-155 (100 nmol/L) or si-PPP2CA (100 nmol/L) for 24 hours. (F) NF-B/p65 activity, assessed by enzyme-linked immunosorbent assay, in HCT cells transfected with NT (100 nmol/L) and as-miR-NC (100 nmol/L), as-miR-21 (100 nmol/L), as-miR-155 (100 nmol/L), or with 10 nmol/L of an AKT pharmacologic inhibitor (MK-2206).
Article Snippet: Materials and Methods Antibodies and Reagents We used the following antibodies and reagents: phos- pho–NF- B/p65 (Ser536) (1:500, 3031; Cell Signaling, Inc, Bevrly, MA), NF- B p65 (1:1,000, ab7970; Abcam, Inc, Cambridge, A), PTEN (1:300, 9559; Cell Signaling, Inc),
Techniques: Binding Assay, Luciferase, Activity Assay, Transfection, Western Blot, Phospho-proteomics, Enzyme-linked Immunosorbent Assay
Journal: Gastroenterology
Article Title: Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors.
doi: 10.1053/j.gastro.2011.07.038
Figure Lengend Snippet: Figure 6. NT affects the tumorigenicity and invasiveness of colon cancer cells through regulation of miR-21 and miR-155 pathways. (A) Number of colonies and (B) invading cells in NT-treated HCT116, DLD1, and SW480 cells in which miR-21 and/or miR-155 were knocked down. (C) NT effects on tumor volume in a HCT116-xenograft model described in the Materials and Methods section. The P value indicates differences between NT/as-miR-NC–treated mice vs NT/as-miR-21/as-miR-155–treated mice. (D) PTEN, SOCS1, and PPP2CA mRNA levels in NT-treated HCT-116- xenograft tumors (day 35).
Article Snippet: Materials and Methods Antibodies and Reagents We used the following antibodies and reagents: phos- pho–NF- B/p65 (Ser536) (1:500, 3031; Cell Signaling, Inc, Bevrly, MA), NF- B p65 (1:1,000, ab7970; Abcam, Inc, Cambridge, A), PTEN (1:300, 9559; Cell Signaling, Inc),
Techniques: