plasma concentrations Search Results


insulin concentrations in effluent and plasma samples  (Mercodia Inc)
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plasma triiodothyronine concentration  (Comline Elektronik Elektrotechnik)
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plasma urea, na+, cl–, k+, mg2+ and ca2+ concentrations  (IDEXX)
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plasma retinol and - carotene concentrations  (Johns Hopkins HealthCare)
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Johns Hopkins HealthCare plasma retinol and - carotene concentrations
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hs-ctni plasma concentrations  (Abbott Laboratories)
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lipids at 1um concentration in serum or plasma  (Metabolon Inc)
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plasma concentrations  (Alturas Analytics Inc)
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Alturas Analytics Inc plasma concentrations
Plasma pharmacokinetic parameters
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plasma cfdna concentration  (NEN Life Science)
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NEN Life Science plasma cfdna concentration
Plasma <t>cfDNA</t> concentration ( A ), cfDNA <t>Alu</t> <t>hypomethylation</t> ( B ), and LINE-1 cfDNA integrity ( C ) in the healthy control group (green) and patients with metastatic NEN (grey). Deceased patients are marked in red, patients lost to follow-up in black. * p < 0.05; ** p < 0.005 in the Mann–Whitney U-test.
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Image Search Results


Plasma pharmacokinetic parameters

Journal: Clinical and Translational Science

Article Title: A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects

doi: 10.1111/cts.13271

Figure Lengend Snippet: Plasma pharmacokinetic parameters

Article Snippet: Plasma concentrations of rilzabrutinib and moxifloxacin were quantified by Alturas Analytics Inc. (Moscow, ID, USA).

Techniques: Clinical Proteomics, Positive Control

Effects of rilzabrutinib on electrocardiogram (ECG) parameters across timepoints over 24 h after administration of rilzabrutinib 400 mg (blue line), rilzabrutinib 400 mg + ritonavir 100 mg (red line), placebo (gray line), or moxifloxacin (green line) in Part B. (a) Change from baseline in heart rate (ΔHR) and (b) mean change from baseline in QTcF interval over time using Fridericia's formula (ΔQTcF)

Journal: Clinical and Translational Science

Article Title: A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects

doi: 10.1111/cts.13271

Figure Lengend Snippet: Effects of rilzabrutinib on electrocardiogram (ECG) parameters across timepoints over 24 h after administration of rilzabrutinib 400 mg (blue line), rilzabrutinib 400 mg + ritonavir 100 mg (red line), placebo (gray line), or moxifloxacin (green line) in Part B. (a) Change from baseline in heart rate (ΔHR) and (b) mean change from baseline in QTcF interval over time using Fridericia's formula (ΔQTcF)

Article Snippet: Plasma concentrations of rilzabrutinib and moxifloxacin were quantified by Alturas Analytics Inc. (Moscow, ID, USA).

Techniques:

Placebo‐corrected change from baseline QTcF (ΔΔQTcF) <xref ref-type= a (Part B)" width="100%" height="100%">

Journal: Clinical and Translational Science

Article Title: A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects

doi: 10.1111/cts.13271

Figure Lengend Snippet: Placebo‐corrected change from baseline QTcF (ΔΔQTcF) a (Part B)

Article Snippet: Plasma concentrations of rilzabrutinib and moxifloxacin were quantified by Alturas Analytics Inc. (Moscow, ID, USA).

Techniques:

Treatment‐related treatment‐emergent adverse events (Part B)

Journal: Clinical and Translational Science

Article Title: A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects

doi: 10.1111/cts.13271

Figure Lengend Snippet: Treatment‐related treatment‐emergent adverse events (Part B)

Article Snippet: Plasma concentrations of rilzabrutinib and moxifloxacin were quantified by Alturas Analytics Inc. (Moscow, ID, USA).

Techniques: Infection

Plasma cfDNA concentration ( A ), cfDNA Alu hypomethylation ( B ), and LINE-1 cfDNA integrity ( C ) in the healthy control group (green) and patients with metastatic NEN (grey). Deceased patients are marked in red, patients lost to follow-up in black. * p < 0.05; ** p < 0.005 in the Mann–Whitney U-test.

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: Plasma cfDNA concentration ( A ), cfDNA Alu hypomethylation ( B ), and LINE-1 cfDNA integrity ( C ) in the healthy control group (green) and patients with metastatic NEN (grey). Deceased patients are marked in red, patients lost to follow-up in black. * p < 0.05; ** p < 0.005 in the Mann–Whitney U-test.

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Clinical Proteomics, Concentration Assay, Control, MANN-WHITNEY

Plasma cfDNA concentration ( A ), cfDNA hypomethylation ( B ), and cfDNA integrity ( C ) with respect to tumor burden (no tumor, low, moderate, or high tumor burden) * p < 0.05.; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: Plasma cfDNA concentration ( A ), cfDNA hypomethylation ( B ), and cfDNA integrity ( C ) with respect to tumor burden (no tumor, low, moderate, or high tumor burden) * p < 0.05.; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Clinical Proteomics, Concentration Assay

Receiver operating characteristic (ROC) curves to distinguish between healthy controls and patients with advanced NEN disease ( A ) and between presumably cured NEN patients and patients with advanced NEN ( B ) for cfDNA concentration ( left ), percentage of cfDNA hypomethylation ( middle ), and cfDNA integrity ( right ).

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: Receiver operating characteristic (ROC) curves to distinguish between healthy controls and patients with advanced NEN disease ( A ) and between presumably cured NEN patients and patients with advanced NEN ( B ) for cfDNA concentration ( left ), percentage of cfDNA hypomethylation ( middle ), and cfDNA integrity ( right ).

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Concentration Assay

Multiparametric ROC analysis using plasma cfDNA concentration, percentage of cfDNA hypomethylation, and cfDNA integrity to estimate the strength of the model to discriminate between ( A ) healthy controls and NEN patients with advanced disease or between ( B ) presumably cured NEN patients and patients with advanced NEN disease.

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: Multiparametric ROC analysis using plasma cfDNA concentration, percentage of cfDNA hypomethylation, and cfDNA integrity to estimate the strength of the model to discriminate between ( A ) healthy controls and NEN patients with advanced disease or between ( B ) presumably cured NEN patients and patients with advanced NEN disease.

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Clinical Proteomics, Concentration Assay

ROC analysis of plasma cfDNA concentration ( A , B ), Alu hypomethylation ( C , D ), and LINE-1 integrity ( E , F ) for distinguishing healthy controls ( A , C , E ), or cured patients ( B , D , F ) from patients with low, moderate, and high tumor burden (TB), along with the area under the curve (AUC), for sensitivities and specificities see .

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: ROC analysis of plasma cfDNA concentration ( A , B ), Alu hypomethylation ( C , D ), and LINE-1 integrity ( E , F ) for distinguishing healthy controls ( A , C , E ), or cured patients ( B , D , F ) from patients with low, moderate, and high tumor burden (TB), along with the area under the curve (AUC), for sensitivities and specificities see .

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Clinical Proteomics, Concentration Assay

Multiparametric ROC analysis using cfDNA concentration, percentage of Alu hypomethylation, and LINE-1 integrity to estimate the strength of the model to discriminate between ( A ) healthy controls and NEN patients or ( B ) presumably cured NEN patients and patients with low, moderate, and high tumor burden (TB), along with the area under the curve (AUC), for sensitivities and specificities see .

Journal: Cancers

Article Title: Quantitative Analysis of Plasma Cell-Free DNA and Its DNA Integrity and Hypomethylation Status as Biomarkers for Tumor Burden and Disease Progression in Patients with Metastatic Neuroendocrine Neoplasias

doi: 10.3390/cancers14041025

Figure Lengend Snippet: Multiparametric ROC analysis using cfDNA concentration, percentage of Alu hypomethylation, and LINE-1 integrity to estimate the strength of the model to discriminate between ( A ) healthy controls and NEN patients or ( B ) presumably cured NEN patients and patients with low, moderate, and high tumor burden (TB), along with the area under the curve (AUC), for sensitivities and specificities see .

Article Snippet: In conclusion, we found plasma cfDNA concentration, integrity, and hypomethylation in metastatic NEN patients to be very promising and easy to assess parameters for a “liquid biopsy” to evaluate patients with neuroendocrine neoplasms during the course of their disease.

Techniques: Concentration Assay