pinsr Search Results


93
Santa Cruz Biotechnology p insulin receptor substrate 1
P Insulin Receptor Substrate 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher anti-pinsr/igf-ir
Anti Pinsr/Igf Ir, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc rabbit polyclonal anti p insulin receptor substrate 1
Rabbit Polyclonal Anti P Insulin Receptor Substrate 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc pakt (pt308) antibody
XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, <t>IRS1</t> tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.
Pakt (Pt308) Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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Cell Signaling Technology Inc anti– p -insulin receptor
XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, <t>IRS1</t> tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.
Anti– P Insulin Receptor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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96
Santa Cruz Biotechnology anti p insulin receptor b subunit
XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, <t>IRS1</t> tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.
Anti P Insulin Receptor B Subunit, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc p insulin receptor igf1r beta
XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, <t>IRS1</t> tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.
P Insulin Receptor Igf1r Beta, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc p insulin receptor substrate 1
XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, <t>IRS1</t> tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.
P Insulin Receptor Substrate 1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/p insulin receptor substrate 1/product/Cell Signaling Technology Inc
Average 95 stars, based on 1 article reviews
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Cell Signaling Technology Inc phospho insulin receptor pinsr β
Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of <t>phospho-InsR-β</t> <t>Tyr1361</t> ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)
Phospho Insulin Receptor Pinsr β, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc anti-pinsr /igf-ir
Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of <t>phospho-InsR-β</t> <t>Tyr1361</t> ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)
Anti Pinsr /Igf Ir, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc anti-pinsr tyr1150/1151
Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of <t>phospho-InsR-β</t> <t>Tyr1361</t> ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)
Anti Pinsr Tyr1150/1151, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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91
Biorbyt p insulin receptor
Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of <t>phospho-InsR-β</t> <t>Tyr1361</t> ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)
P Insulin Receptor, supplied by Biorbyt, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, IRS1 tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.

Journal: Diabetes

Article Title: X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell Function

doi: 10.2337/db12-1747

Figure Lengend Snippet: XBP1 deficiency impairs insulin signaling. Western blotting for insulin receptor (IR) tyrosine 972 (Y) phosphorylation (pIR), IR, IRS1 tyrosine 896 (Y) phosphorylation, IRS1 Ser 307 (Ser) phosphorylation, total IRS1, Akt Thr 308 phosphorylation, Akt Ser 473 phosphorylation, total Akt, and β-actin (loading control) in control or αXBPKD cell lines ( A ) and in control or αXBPOE cell lines ( D ) before and after insulin (ins) treatment for 10 min (100 nmol/L). Quantification of pIRS1(Y)/IRS1, pIRS1(Ser)/IRS1, pAkt(T308)/Akt, and pAkt(S473)/Akt in control or αXBPKD cell lines ( B ) and in control or αXBPOE cell lines ( E ). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Glucagon secretion from control or αXBPKD cell lines ( C ) and control or αXBPOE cell lines ( F ) was assessed by static incubation for 60 min under various glucose concentrations, without or with 100 nmol/L insulin (Ins), and expressed per microgram of total DNA ( n = 3–6 in each group). Data are expressed as means ± SEM. * P < 0.05, ** P < 0.01; n.s., not significant.

Article Snippet: Binding immunoglobulin protein (BiP), IRE1α, pPERK, pJNK, JNK, p-insulin receptor substrate 1 (IRS1) (pS307), pAkt (pT308), pAkt (pS473), total Akt, forkhead box O1 (FoxO1), and cleaved caspase 3 antibodies were from Cell Signaling. pIRE1α antibody is from Novus Biologicals.

Techniques: Western Blot, Phospho-proteomics, Control, Incubation

Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of phospho-InsR-β Tyr1361 ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)

Journal: BMC Complementary and Alternative Medicine

Article Title: Jia-Wei-Jiao-Tai-Wan ameliorates type 2 diabetes by improving β cell function and reducing insulin resistance in diabetic rats

doi: 10.1186/s12906-017-2016-5

Figure Lengend Snippet: Effect of JWJTW on insulin signaling in skeletal muscle of diabetic rats. Western blot analysis of phospho-InsR-β Tyr1361 ( a ), phospho-IRS-1 Tyr612 and phospho-IRS-1 Ser307 ( b ), PI3K (p85) ( c ) and GLUT4 ( d ). * p < 0.05, ** p < 0.01, *** p < 0.001 ( n = 5)

Article Snippet: The antibodies used in this study were purchased from the following manufacturers: the antibody against pancreatic and duodenal homeobox 1 (PDX-1) was purchased from Chemi-con (USA); against insulin and against insulin receptor (InsR-β) from Abcam (UK); against insulin receptor substrate (IRS)-1 from Upstate (USA); against phospho-insulin receptor substrate (pIRS)-1(Ser307) and pIRS-1(Tyr612), phospho-insulin receptor (pInsR)-β (Tyr1361), phosphatidylinositol 3-kinase (PI3K) (p85) and glucose transporter 4 (GLUT4) from Cell Signaling Technology (CST, USA) and against GAPDH from Wuhan Gugeshengwu Technology Co., Ltd. (China).

Techniques: Western Blot