pim3 Search Results


85
Thermo Fisher gene exp pim3 hs00420511 g1
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Gene Exp Pim3 Hs00420511 G1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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96
Carna Inc gst
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
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91
OriGene pim3
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Pim3, supplied by OriGene, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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85
Thermo Fisher copy number variation pim3 mm00438616 cn
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Copy Number Variation Pim3 Mm00438616 Cn, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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91
Bioss anti pim1
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Anti Pim1, supplied by Bioss, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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85
Thermo Fisher gene exp pim3 rn00575067 m1
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Gene Exp Pim3 Rn00575067 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 85/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 85 stars, based on 1 article reviews
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88
Thermo Fisher gene exp pim3 mm00446876 m1
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Gene Exp Pim3 Mm00446876 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 88 stars, based on 1 article reviews
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94
OriGene rc212690 software
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Rc212690 Software, supplied by OriGene, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Proteintech pim 3 professor naofumi mukaida
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Pim 3 Professor Naofumi Mukaida, supplied by Proteintech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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96
Carna Inc pim3
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Pim3, supplied by Carna Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Perimed Inc periscan pim 3
( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and <t>PIM3</t> in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.
Periscan Pim 3, supplied by Perimed Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and PIM3 in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.

Journal: Oncotarget

Article Title: Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447

doi: 10.18632/oncotarget.11457

Figure Lengend Snippet: ( A ) IC 50 values of cell lines to PIM447. IC 50 values determined from luminescent viability with the Cell Titer Glo reagent. Indicated cell lines were treated with serial dilutions of PIM447 for 72 hours. Shown is the mean of four replicates ± SEM. ( B ) IC 50 values of ABC and GCB DLBCL cell lines, compared with two-tailed T test. ( C ) mRNA expression of PIM1 , PIM2 and PIM3 in ABC-derived vs. other DLBCL cell lines, compared with two-tailed T test. qRT-PCR was performed on cDNA isolated from each cell line. 2 −ΔΔCT normalized to GAPDH ( D ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for PIM447 and AZD1208 being 10 μM. Shown is the mean of four replicates ± SEM. ( E ) IC 50 values calculated from cell viability assays of indicated cell lines, with the top concentration for AEB071 being 10 μM and 1 μM for Ibrutinib. Shown is the mean of four replicates ± SEM. ( F ) ABC DLBCL cell lines, grouped based on drug sensitivity, with known somatic mutations.

Article Snippet: Probes used were: Hs0165498_m1 (PIM1), Hs00179139_m1 (PIM2), Hs00420511_m1 (PIM3), and Hs02758991_g1 (GAPDH) for normalizing the data, using the 2 −ΔΔCT .

Techniques: Two Tailed Test, Expressing, Derivative Assay, Quantitative RT-PCR, Isolation, Concentration Assay