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Palobiofarma
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Novartis
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Novartis
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Novartis
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TESARO Inc
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AstraZeneca ltd
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Spartalizumab PDCD1 PD1 CD279 Antibody Monoclonal Drug Analogue
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Spartalizumab is a humanized immunoglobulin 4 monoclonal antibody that binds to PD-1 with subanomolar activity and blocks interactions with PD-L1 and PD-L2. Spartalizumab can be used in the study of thyroid undifferentiated carcinoma (ATC).Purity>95% (SDS-PAGE&SEC)Endotoxin
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Image Search Results
Journal: Immune Network
Article Title: Adenosine Blockage in Tumor Microenvironment and Improvement of Cancer Immunotherapy
doi: 10.4110/in.2019.19.e23
Figure Lengend Snippet: Clinical trials with adenosine pathway inhibitors combined with an immune check inhibitor in cancer
Article Snippet: A2AR , PFB509 ,
Techniques: Clinical Proteomics
Journal: Frontiers in Immunology
Article Title: Combinatorial blockade for cancer immunotherapy: targeting emerging immune checkpoint receptors
doi: 10.3389/fimmu.2023.1264327
Figure Lengend Snippet: Clinical trials testing combined targeting of ICRs.
Article Snippet: ,
Techniques: Clinical Proteomics, Activity Assay, Biomarker Discovery
Journal: Frontiers in Physiology
Article Title: Purinergic and Adenosinergic Signaling in Pancreatobiliary Diseases
doi: 10.3389/fphys.2022.849258
Figure Lengend Snippet: Clinical trials evaluating the potential use of purinergic mediators as targets for hepatopancreatobiliary tumors.
Article Snippet: CD73 +/− A2AAR , NZV930 (anti-CD73 Ab) +/−
Techniques: Clinical Proteomics
Journal: Acta Pharmaceutica Sinica. B
Article Title: Application of immune checkpoint targets in the anti-tumor novel drugs and traditional Chinese medicine development
doi: 10.1016/j.apsb.2021.03.004
Figure Lengend Snippet: The mechanism of immunotherapy regulation based on immune checkpoint pathways (PD-1 and PD-L1).
Article Snippet: TIM-3 antibodies include TSR-022 from
Techniques:
Journal: Acta Pharmaceutica Sinica. B
Article Title: Application of immune checkpoint targets in the anti-tumor novel drugs and traditional Chinese medicine development
doi: 10.1016/j.apsb.2021.03.004
Figure Lengend Snippet: Immune mechanism of TCMs as PD-1/PDL-1 inhibitors.
Article Snippet: TIM-3 antibodies include TSR-022 from
Techniques: Expressing, Cell Culture, Isolation, Transplantation Assay, In Vitro, In Vivo