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CELLnTEC Advanced Cell Systems AG
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Image Search Results
Journal: International Journal for Parasitology: Drugs and Drug Resistance
Article Title: In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts
doi: 10.1016/j.ijpddr.2021.05.001
Figure Lengend Snippet: Structure and in vitro activities of BKI-1748 against N. caninum (Nc-β-gal) and T. gondii (Tg-β-gal). (A) molecular structure of BKI-1748, MW = molecular weight; EC 50 = concentration of half maximal proliferation inhibition; *toxicity levels against human foreskin fibroblasts (HFF) and zebrafish embryos were determined previously [22]. (B,C) Dose-response curves for Neospora and Toxoplasma tachyzoites grown in HFF.
Article Snippet:
Techniques: In Vitro, Molecular Weight, Concentration Assay, Inhibition
Journal: International Journal for Parasitology: Drugs and Drug Resistance
Article Title: In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts
doi: 10.1016/j.ijpddr.2021.05.001
Figure Lengend Snippet: Litter size, parasite burden, neonatal and postnatal mortality rates of N. caninum infected mice treated with BKI-1748.
Article Snippet:
Techniques: Infection