pbpk Search Results


pbpk modelling  (Certara L.P)
86
Certara L.P pbpk modelling
Pbpk Modelling, supplied by Certara L.P, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
pbpk modelling - by Bioz Stars, 2026-06
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pbpk models for the five macrolide antibiotics  (DILIsym Services Inc)
90
DILIsym Services Inc pbpk models for the five macrolide antibiotics
Toxicity Parameters Utilized in the Simulation of the Five <t> Macrolide </t> Compounds in DILIsym v5A
Pbpk Models For The Five Macrolide Antibiotics, supplied by DILIsym Services Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pbpk models for the five macrolide antibiotics - by Bioz Stars, 2026-06
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m83 mice  (ANSES laboratories)
90
ANSES laboratories m83 mice
Toxicity Parameters Utilized in the Simulation of the Five <t> Macrolide </t> Compounds in DILIsym v5A
M83 Mice, supplied by ANSES laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
m83 mice - by Bioz Stars, 2026-06
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physiologically based pharmacokinetics (pbpk)  (DILIsym Services Inc)
90
DILIsym Services Inc physiologically based pharmacokinetics (pbpk)
Toxicity Parameters Utilized in the Simulation of the Five <t> Macrolide </t> Compounds in DILIsym v5A
Physiologically Based Pharmacokinetics (Pbpk), supplied by DILIsym Services Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/physiologically based pharmacokinetics (pbpk)/product/DILIsym Services Inc
Average 90 stars, based on 1 article reviews
physiologically based pharmacokinetics (pbpk) - by Bioz Stars, 2026-06
90/100 stars
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pbpk model  (Biopharm GmbH)
90
Biopharm GmbH pbpk model
Toxicity Parameters Utilized in the Simulation of the Five <t> Macrolide </t> Compounds in DILIsym v5A
Pbpk Model, supplied by Biopharm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pbpk model/product/Biopharm GmbH
Average 90 stars, based on 1 article reviews
pbpk model - by Bioz Stars, 2026-06
90/100 stars
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hybrid cfd pbpk models for prediction of nasal corticosteroid deposition, absorption, and bioavailability  (Applied Research Associates Inc)
90
Applied Research Associates Inc hybrid cfd pbpk models for prediction of nasal corticosteroid deposition, absorption, and bioavailability
Toxicity Parameters Utilized in the Simulation of the Five <t> Macrolide </t> Compounds in DILIsym v5A
Hybrid Cfd Pbpk Models For Prediction Of Nasal Corticosteroid Deposition, Absorption, And Bioavailability, supplied by Applied Research Associates Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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pbpk submodels  (DILIsym Services Inc)
90
DILIsym Services Inc pbpk submodels
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Pbpk Submodels, supplied by DILIsym Services Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pbpk submodels - by Bioz Stars, 2026-06
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avian pbpk model  (Baier labs)
90
Baier labs avian pbpk model
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Avian Pbpk Model, supplied by Baier labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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pbpk modeling tools pk-sim  (Bayer AG)
90
Bayer AG pbpk modeling tools pk-sim
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Pbpk Modeling Tools Pk Sim, supplied by Bayer AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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physiologically-based pharmacokinetic (pbpk) models  (Johns Hopkins HealthCare)
90
Johns Hopkins HealthCare physiologically-based pharmacokinetic (pbpk) models
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Physiologically Based Pharmacokinetic (Pbpk) Models, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
physiologically-based pharmacokinetic (pbpk) models - by Bioz Stars, 2026-06
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inhalation pbpk models  (AstraZeneca ltd)
90
AstraZeneca ltd inhalation pbpk models
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Inhalation Pbpk Models, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pbpk modeling  (Denka Co Ltd)
90
Denka Co Ltd pbpk modeling
List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)
Pbpk Modeling, supplied by Denka Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Toxicity Parameters Utilized in the Simulation of the Five Macrolide Compounds in DILIsym v5A

Journal: Pharmaceutical Research

Article Title: Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

doi: 10.1007/s11095-019-2582-y

Figure Lengend Snippet: Toxicity Parameters Utilized in the Simulation of the Five Macrolide Compounds in DILIsym v5A

Article Snippet: PBPK models for the five macrolide antibiotics were constructed within DILIsym to describe disposition of macrolides in humans.

Techniques: Inhibition

Most Likely Mechanism of Toxicity Suggested by the Simulation Results for Each Macrolide Antibiotic

Journal: Pharmaceutical Research

Article Title: Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling

doi: 10.1007/s11095-019-2582-y

Figure Lengend Snippet: Most Likely Mechanism of Toxicity Suggested by the Simulation Results for Each Macrolide Antibiotic

Article Snippet: PBPK models for the five macrolide antibiotics were constructed within DILIsym to describe disposition of macrolides in humans.

Techniques: Inhibition

List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)

Journal: CPT: Pharmacometrics & Systems Pharmacology

Article Title: Elucidating Differences in the Hepatotoxic Potential of Tolcapone and Entacapone With DILIsym ® , a Mechanistic Model of Drug‐Induced Liver Injury

doi: 10.1002/psp4.12053

Figure Lengend Snippet: List of parameters varied in the SimPops™ and results of multiple‐regression analysis in SimPops™ administered tolcapone (200 mg t.i.d. for 1 week)

Article Snippet: Via the use of PBPK submodels developed to describe the disposition of tolcapone and entacapone, DILIsym ® predicted lower hepatic exposure for entacapone than for tolcapone for clinically relevant dosing regimens of each compound.

Techniques: