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Image Search Results
Figure S4 ). " width="100%" height="100%">
Journal: iScience
Article Title: Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence
doi: 10.1016/j.isci.2022.104034
Figure Lengend Snippet: Time-course transcriptomic profiling reveals detailed molecular events in the febrile phase of DENV infection (A) Principal Component Analysis (PCA) of overall transcriptomic patterns among the ten PBMC samples. Colors represent the time points of DENV infection; shapes represent different severities. (B) Heatmap showing the relative expression of highly variable genes (HVGs), from the union of the top 500 genes in PC1 and PC2 from (A) (see ). (C) Dotplots illustrating the relative expression of HVGs over the course of DENV infection. The biological processes (BPs) of HVGs that are common across the four cell types are in red; monocyte-specific BPs are in blue, and B cell-specific BPs are in green. The relative expression is indicated by the color intensity (see ). (D) UMAP feature plots of the relative signature scores of HVGs that are associated in that particular BPs (see also
Article Snippet: Dataset: 4k PBMCs from a healthy donor ,
Techniques: Infection, Expressing
Figure S6 and ). (B) Relative abundances of Effector T cells (upper panel) and Naive/Memory T cells (lower panel). (C) Relative expression of the top 20 differentially expressed genes (DEGs) between each of the subpopulations and the rest of effector-like T cells. (D) Average expression of tissue-homing genes in Effector T cells. The dot sizes represent the proportion of cells expressing the genes. (E) UMAP plots showing the Effector CD8 (upper panel) and CD4 (lower panel) T cells. Black lines represent pseudotime constructed by Monocle3 ( Journal: iScience
Article Title: Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence
doi: 10.1016/j.isci.2022.104034
Figure Lengend Snippet: Functional characterisation of T cell subpopulations during DENV infection (A) UMAP plots of integrated T cell transcriptome profiles from the ten PBMC samples (see also
Article Snippet: Dataset: 4k PBMCs from a healthy donor ,
Techniques: Functional Assay, Infection, Expressing, Construct
Journal: iScience
Article Title: Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence
doi: 10.1016/j.isci.2022.104034
Figure Lengend Snippet:
Article Snippet: Dataset: 4k PBMCs from a healthy donor ,
Techniques: Control, Recombinant, Isolation, Saline, Sequencing, Gene Expression, Software