paurka Search Results


p aur a th288 c39d8  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc p aur a th288 c39d8
P Aur A Th288 C39d8, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/p aur a th288 c39d8/product/Cell Signaling Technology Inc
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p aur a th288 c39d8 - by Bioz Stars, 2026-03
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aurka protein  (Cell Signaling Technology Inc)
90
Cell Signaling Technology Inc aurka protein
Aurka Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aurka protein/product/Cell Signaling Technology Inc
Average 90 stars, based on 1 article reviews
aurka protein - by Bioz Stars, 2026-03
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anti-phosphorylated aurora (thr288  (Thermo Fisher)
90
Thermo Fisher anti-phosphorylated aurora (thr288
Sperm collected from the caput (A), corpus (B) and cauda (C) were triple stained with phosphor-Aurora A <t>(Thr288)</t> (red), conjugated PNA-Lectin AF488 (green) and DAPI to visualize the nuclei (blue). Active AURKA is also arranged into two parallel lines. However, expression is localized to the midpiece of epididymal sperm. (D) Expression of active AURKA was significantly increased in cauda sperm when compared to both the caput p<0.0019 and corpus p<0.0237 (D). Scale bars indicate 10μM.
Anti Phosphorylated Aurora (Thr288, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-phosphorylated aurora (thr288/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
anti-phosphorylated aurora (thr288 - by Bioz Stars, 2026-03
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paurka b c  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc paurka b c
Sperm collected from the caput (A), corpus (B) and cauda (C) were triple stained with phosphor-Aurora A <t>(Thr288)</t> (red), conjugated PNA-Lectin AF488 (green) and DAPI to visualize the nuclei (blue). Active AURKA is also arranged into two parallel lines. However, expression is localized to the midpiece of epididymal sperm. (D) Expression of active AURKA was significantly increased in cauda sperm when compared to both the caput p<0.0019 and corpus p<0.0237 (D). Scale bars indicate 10μM.
Paurka B C, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/paurka b c/product/Cell Signaling Technology Inc
Average 96 stars, based on 1 article reviews
paurka b c - by Bioz Stars, 2026-03
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paurka  (Cell Signaling Technology Inc)
98
Cell Signaling Technology Inc paurka
Sperm collected from the caput (A), corpus (B) and cauda (C) were triple stained with phosphor-Aurora A <t>(Thr288)</t> (red), conjugated PNA-Lectin AF488 (green) and DAPI to visualize the nuclei (blue). Active AURKA is also arranged into two parallel lines. However, expression is localized to the midpiece of epididymal sperm. (D) Expression of active AURKA was significantly increased in cauda sperm when compared to both the caput p<0.0019 and corpus p<0.0237 (D). Scale bars indicate 10μM.
Paurka, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/paurka/product/Cell Signaling Technology Inc
Average 98 stars, based on 1 article reviews
paurka - by Bioz Stars, 2026-03
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anti-phosphorylated aurora a (t288)  (Cell Signaling Technology Inc)
90
Cell Signaling Technology Inc anti-phosphorylated aurora a (t288)
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Anti Phosphorylated Aurora A (T288), supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-phosphorylated aurora a (t288)/product/Cell Signaling Technology Inc
Average 90 stars, based on 1 article reviews
anti-phosphorylated aurora a (t288) - by Bioz Stars, 2026-03
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threonine 288 paurka  (Bethyl)
90
Bethyl threonine 288 paurka
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Threonine 288 Paurka, supplied by Bethyl, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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threonine 288 paurka - by Bioz Stars, 2026-03
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nitrogen (purity 6.0  (Linde Gas Gmbh)
90
Linde Gas Gmbh nitrogen (purity 6.0
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Nitrogen (Purity 6.0, supplied by Linde Gas Gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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nitrogen (purity 6.0 - by Bioz Stars, 2026-03
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paurka nb100-2371 antibody  (Novus Biologicals)
90
Novus Biologicals paurka nb100-2371 antibody
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Paurka Nb100 2371 Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/paurka nb100-2371 antibody/product/Novus Biologicals
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paurka nb100-2371 antibody - by Bioz Stars, 2026-03
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ventyo machine  (Linde Gas Gmbh)
90
Linde Gas Gmbh ventyo machine
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Ventyo Machine, supplied by Linde Gas Gmbh, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ventyo machine/product/Linde Gas Gmbh
Average 90 stars, based on 1 article reviews
ventyo machine - by Bioz Stars, 2026-03
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paurka thr288  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc paurka thr288
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Paurka Thr288, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/paurka thr288/product/Cell Signaling Technology Inc
Average 94 stars, based on 1 article reviews
paurka thr288 - by Bioz Stars, 2026-03
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bromophenol blue  (Fluka Chemical)
90
Fluka Chemical bromophenol blue
Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A <t>(T288)</t> phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.
Bromophenol Blue, supplied by Fluka Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Sperm collected from the caput (A), corpus (B) and cauda (C) were triple stained with phosphor-Aurora A (Thr288) (red), conjugated PNA-Lectin AF488 (green) and DAPI to visualize the nuclei (blue). Active AURKA is also arranged into two parallel lines. However, expression is localized to the midpiece of epididymal sperm. (D) Expression of active AURKA was significantly increased in cauda sperm when compared to both the caput p<0.0019 and corpus p<0.0237 (D). Scale bars indicate 10μM.

Journal: Biochemical and biophysical research communications

Article Title: Novel Localization of Aurora A Kinase in Mouse Testis Suggests Multiple Roles in Spermatogenesis

doi: 10.1016/j.bbrc.2018.05.170

Figure Lengend Snippet: Sperm collected from the caput (A), corpus (B) and cauda (C) were triple stained with phosphor-Aurora A (Thr288) (red), conjugated PNA-Lectin AF488 (green) and DAPI to visualize the nuclei (blue). Active AURKA is also arranged into two parallel lines. However, expression is localized to the midpiece of epididymal sperm. (D) Expression of active AURKA was significantly increased in cauda sperm when compared to both the caput p<0.0019 and corpus p<0.0237 (D). Scale bars indicate 10μM.

Article Snippet: Sperm were blocked in 3% BSA for 1 hour at room temperature then stained with anti-Aurora A antibody (IHC, 1:50; Bethyl Laboratories; Montgomery, TX) or anti-phosphorylated Aurora A (Thr288) (1:50; ThermoFisher; Rochester, NY) along with PNA-lectin conjugated to Alexa Fluor 488 (1:200; ThermoFisher; Rochester, NY) to visualize the acrosome.

Techniques: Staining, Expressing

Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A (T288) phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.

Journal: BMC Cancer

Article Title: Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC

doi: 10.1186/1471-2407-10-461

Figure Lengend Snippet: Aurora B kinase selective inhibitor, AZD1152-HQPA, shows antiproliferative effects in HCC cells . (A) Concentration-dependent inhibitory effects of AZD1152-HQPA on cell viability in Huh-7 and Hep3B cell lines. Cells were treated with AZD1152-HQPA at 1, 5, 25, and 125 nM in 10% FBS-supplemented medium for 72 hours; cell viability was determined by trypan blue assay. Columns : means; bars : SD ( n = 3). §, p < 0.05; *, p < 0.01 (compared with untreated controls). The changes in cell counts and morphologic features are shown in the lower panels (magnification, × 100). (B) Huh-7 and Hep3B cells were treated with AZD1152-HQPA for 24 hours. The cell lysates were then immunoblotted. Histone H3 (Ser10) phosphorylation, the key substrate of Aurora B signaling, was downregulated in a concentration-dependent manner. Aurora A (T288) phosphorylation, the key substrate of Aurora A signaling, was not repressed by AZD1152-HQPA treatments.

Article Snippet: The following primary antibodies were used: anti-Aurora B (Novus Biologicals, Littleton, CO, USA), anti-Aurora A (Novus Biologicals), anti-α-tubulin antibody (Sigma-Aldrich, St. Louis, MO, USA), anti-phosphorylated histone H3 (Ser10) (Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA), and anti-phosphorylated Aurora A (T288) (Cell Signaling Technology, Inc., Danvers, MA, USA).

Techniques: Concentration Assay, Phospho-proteomics