otenabant Search Results


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MedChemExpress otenabant
Effect of 3-arm antagonists in modulating GRAB eCB2.0 fluorescence in presence of 300 nM CP55940.
Otenabant, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/otenabant/Otenabant/pmc11084632-210-32-33
Average 94 stars, based on 1 article reviews
otenabant - by Bioz Stars, 2026-09
94/100 stars
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Otenabant is a potent and selective cannabinoid receptor 1 inhibitor with Ki of 0.13 nM.
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Otenabant (CP945598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM.
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Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1.
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Otenabant HCl is a selective and high affinity antagonist of CB1 with Ki value of 0.7 nM.
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Otenabant, also known as CP-945,598, is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesity, but development for this application has been
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Otenabant Hydrochloride
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Effect of 3-arm antagonists in modulating GRAB eCB2.0 fluorescence in presence of 300 nM CP55940.

Journal: International Journal of Molecular Sciences

Article Title: Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRAB eCB2.0 Sensor

doi: 10.3390/ijms25095012

Figure Lengend Snippet: Effect of 3-arm antagonists in modulating GRAB eCB2.0 fluorescence in presence of 300 nM CP55940.

Article Snippet: Chemicals and Reagents: 2-AG (Cayman, Ann Arbor, MI, USA #62160), CP55940 (Cayman #13608), ACEA (Biotechne, Minneapolis, MN, USA: Tocris #1319), SR141716 (MedChem Express, New York, NY, USA: #HY14136), Taranabant (MedChem Express #HY10013), Otenabant (MedChem Express #HY-10871), Ibipinabant (MedChem Express HY-14791), and GAT228 and GAT229 (MilliporeSigma: Burlington, MA, USA #SML1952 and #SML1951).

Techniques: Fluorescence