organoids Search Results


organoid media formulation  (ATCC)
94
ATCC organoid media formulation
Organoid Media Formulation, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cell harvest solution  (R&D Systems)
95
R&D Systems cell harvest solution
Cell Harvest Solution, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bme trevigen 3533 010 02  (Trevigen)
94
Trevigen bme trevigen 3533 010 02
Bme Trevigen 3533 010 02, supplied by Trevigen, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cultrex organoid harvesting solution  (Trevigen)
96
Trevigen cultrex organoid harvesting solution
Cultrex Organoid Harvesting Solution, supplied by Trevigen, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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atcc acs 7105 nicotinamide  (ATCC)
94
ATCC atcc acs 7105 nicotinamide
Atcc Acs 7105 Nicotinamide, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bme  (AMS Biotechnology)
96
AMS Biotechnology bme
Bme, supplied by AMS Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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organoid growth kit 1a  (ATCC)
94
ATCC organoid growth kit 1a
Organoid Growth Kit 1a, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human colorectal cancer organoids  (MedChemExpress)
92
MedChemExpress human colorectal cancer organoids
Human Colorectal Cancer Organoids, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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organoid vitality assay kit  (MedChemExpress)
93
MedChemExpress organoid vitality assay kit
Organoid Vitality Assay Kit, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human hcc organoid culture kit  (MedChemExpress)
94
MedChemExpress human hcc organoid culture kit
Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in <t>HCC</t> organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived <t>HCC</t> <t>SNU-423-CO</t> organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.
Human Hcc Organoid Culture Kit, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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organoids  (Angio-Proteomie)
92
Angio-Proteomie organoids
Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in <t>HCC</t> organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived <t>HCC</t> <t>SNU-423-CO</t> organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.
Organoids, supplied by Angio-Proteomie, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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organoids - by Bioz Stars, 2026-03
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organoid re formed  (MedChemExpress)
94
MedChemExpress organoid re formed
Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in <t>HCC</t> organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived <t>HCC</t> <t>SNU-423-CO</t> organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.
Organoid Re Formed, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in HCC organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived HCC SNU-423-CO organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.

Journal: International Journal of Biological Sciences

Article Title: Combining sorafenib with spermine and sphingosine synergistically enhances anticancer efficacy by modulating metabolic pathways and gut microbiome in hepatocellular carcinoma

doi: 10.7150/ijbs.118753

Figure Lengend Snippet: Clinical relevance of SMOX , CERS1 , and SPHK1 expression and combining effects of sorafenib with spermine or sphingosine in HCC organoids. (A-B) The overall survival rates of liver cancer patients in TCGA were plotted according to the expression levels of the SMOX metabolic enzyme of spermine (A) and the CERS1 and SPHK1 metabolic enzymes of sphingosine (B) using KM Plotter. (C-D) The relative gene expression of SMOX (C) and SPHK1 (D) in normal (left) and tumor (right) tissues from adrenal cancer (Adrenal), acute myeloid leukemia (AML), bladder cancer (Bladder), breast cancer (Breast), colon cancer (Colon), esophageal cancer (Esoph), liver cancer (Liver), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSQ), ovary cancer (Ovary), pancreatic cancer (Pancreas), prostate cancer (Prostate), rectal cancer (Rectum), renal clear cell cancer (RCC), renal CH (RCH), renal PA (RPA), skin cancer (Skin), stomach cancer (Stomach), testis cancer (Testis), thyroid cancer (Thyroid), uterine CS cancer (UCS), and uterine EC (UEC). *: Mann-Whitney p<0.05 and expression >10 in tumor or normal tissue. (E-F) Patient-derived HCC SNU-423-CO organoids were treated with sorafenib with and without spermine or sphingosine for 6 days. (E) Representative images were obtained using a confocal microscope (TS100, Nikon, Tokyo, Japan). Scale bar, 50 μm. ( F ) Organoid formation efficiency and cell viability were assessed by CellTiter-Glo 3D assay. The relative organoid cell viability was plotted. Data are presented as the mean ± SD. ** p < 0.01; *** p < 0.001.

Article Snippet: Patient-derived HCC SNU-423-CO organoids were obtained from KCLB (Seoul, Korea) and maintained using the human HCC organoid culture kit (Med Chem Express, Princeton, NJ, USA), supplemented with 50 ng/ml EGF, 100 ng/ml FGF, 25 ng/ml HGF, 10 mM forskolin, 1 × B27, 10 mM nicotinamide, 5 mM A83-01, 1.25 mM N-acetylcysteine, and 50 mg/ml primocin .

Techniques: Expressing, Gene Expression, MANN-WHITNEY, Derivative Assay, Microscopy