Journal: Investigative Ophthalmology & Visual Science

Article Title: Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

doi: 10.1167/iovs.16-20969

Figure Lengend Snippet: En face SS- and SD-OCTA images from the left eye of a 70-year-old woman with CNV secondary to AMD. All images were processed from the corresponding volumetric datasets using the same algorithms that were applied to a slab that extended from the outer retina to the choriocapillaris and included the removal of the projection artifacts from the retinal vasculature. ( A ) Spectral-domain OCTA 3 × 3-mm 2 scan. ( B ) Spectral-domain OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 1.51 mm 2 . ( C ) Spectral-domain OCTA 3 × 3-mm 2 scan. ( D ) Spectral-domain OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 1.51 mm 2 . ( E ) Spectral-domain OCTA 6 × 6-mm 2 scan. ( F ) Spectral-domain OCTA 6 × 6-mm 2 scan with an outline of the CNV and an area of 1.52 mm 2 . ( G ) Spectral-domain OCTA 6 × 6-mm 2 scan. ( H ) Spectral-domain OCTA 6 × 6-mm 2 scan with an outline of the CNV and an area of 1.13 mm 2 . In this example, the area measurements were similar for the 3 × 3-mm 2 scans, but SS-OCTA imaging showed a larger lesion for the 6 × 6-mm 2 scans.

Article Snippet: Swept-source OCTA was performed using a prototype provided by Carl Zeiss Meditec, Inc.

Techniques: Imaging

Journal: Investigative Ophthalmology & Visual Science

Article Title: Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

doi: 10.1167/iovs.16-20969

Figure Lengend Snippet: En face SS- and SD-OCTA images from the left eye of an 87-year-old woman with CNV secondary to AMD. All images were processed from the corresponding volumetric datasets using the same algorithms that were applied to a slab that extended from the outer retina to the choriocapillaris and included the removal of the projection artifacts from the retinal vasculature. ( A ) Swept-source OCTA 3 × 3-mm 2 scan. ( B ) Swept-source OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 1.25 mm 2 . ( C ) Spectral-domain OCTA 3 × 3-mm 2 scan. ( D ) Spectral-domain OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 0.722 mm 2 . ( E ) Swept-source OCTA 6 × 6-mm 2 scan. ( F ) Swept-source OCTA 6 × 6-mm 2 scan with an outline of the CNV and an area of 1.40 mm 2 . ( G ) Spectral-domain OCTA 6 × 6-mm 2 scan. ( H ) Spectral-domain OCTA 6 × 6-mm 2 scan with an outline of the CNV and an area of 0.535 mm 2 . In this example, SS-OCTA imaging yielded the larger area measurements for both the 3 × 3- and 6 × 6-mm 2 scans compared with SD-OCTA imaging.

Article Snippet: Swept-source OCTA was performed using a prototype provided by Carl Zeiss Meditec, Inc.

Techniques: Imaging

Journal: Investigative Ophthalmology & Visual Science

Article Title: Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

doi: 10.1167/iovs.16-20969

Figure Lengend Snippet: En face SS- and SD-OCTA images from the left eye of a 79-year-old man with CNV secondary to AMD. All images were processed from the corresponding volumetric datasets using the same algorithms that were applied to a slab that extended from the outer retina to the choriocapillaris and included the removal of the projection artifacts from the retinal vasculature. ( A ) Swept-source OCTA 3 × 3-mm 2 scan. ( B ) Swept-source OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 1.75 mm 2 . ( C ) Spectral-domain OCTA 3 × 3-mm 2 scan. ( D ) Spectral-domain OCTA 3 × 3-mm 2 scan with an outline of the CNV and an area of 1.60 mm 2 . ( E ) Swept-source OCTA 6 × 6-mm 2 scan. ( F ) Swept-source OCTA 6 × 6-mm 2 scan with an outline of the CNV and an area of 1.95 mm 2 . ( G ) Spectral-domain OCTA 6 × 6-mm 2 scan. ( H ) Spectral-domain OCTA 6 × 6-mm 2 scan without any outline of the CNV due to the consensus between graders that the lesion borders for the CNV were not clearly demarcated.

Article Snippet: Swept-source OCTA was performed using a prototype provided by Carl Zeiss Meditec, Inc.

Techniques:

Journal: Investigative Ophthalmology & Visual Science

Article Title: Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

doi: 10.1167/iovs.16-20969

Figure Lengend Snippet: Scatter plots comparing area measurements of CNV obtained using 3 × 3- and 6 × 6-mm 2 SS- and SD-OCTA scans. ( A ) Comparison between 3 × 3-mm 2 CNV area measurements from the SS-OCTA and SD-OCTA instruments. Slightly larger CNV areas were measured using the SS-OCTA instrument ( P = 0.047), but the correlation coefficient was good at r = 0.84 ( P < 0.001). ( B ) Comparison between 6 × 6-mm 2 CNV area measurements from the SS-OCTA and SD-OCTA instruments. Larger CNV areas were measured using the SS-OCTA instrument ( P = 0.003), and the correlation coefficient was modest at r = 0.33 ( P = 0.093).

Article Snippet: Swept-source OCTA was performed using a prototype provided by Carl Zeiss Meditec, Inc.

Techniques: Comparison

Journal: Investigative Ophthalmology & Visual Science

Article Title: Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

doi: 10.1167/iovs.16-20969

Figure Lengend Snippet: Bland-Altman plots showing the difference in area measurements of CNV obtained using SS- and SD-OCTA scans with both the 3 × 3- and 6 × 6-mm 2 scan patterns. ( A ) Difference in area measurements between SS-OCTA and SD-OCTA imaging using the 3 × 3-mm 2 scan and the relationship with mean lesion area. ( B ) Difference in area measurements between SS-OCTA and SD-OCTA imaging using the 6 × 6-mm 2 scan and the relationship with mean lesion area.

Article Snippet: Swept-source OCTA was performed using a prototype provided by Carl Zeiss Meditec, Inc.

Techniques: Imaging