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Image Search Results
Journal: Journal of Cellular and Molecular Medicine
Article Title: Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress
doi: 10.1111/jcmm.15231
Figure Lengend Snippet: The characteristics of primers used for analysis of methylation levels in the promoter regions of the studied genes
Article Snippet: Expression of SOD1 (assay ID: Rn00566938_m1), SOD2 (assay ID: Rn00690588_g1), Gpx1 (assay ID: Rn00577994_g1), Gpx4 (assay ID: Rn00820818_g1), CAT (assay ID: Rn00560930_m1), NOS1 (assay ID:
Techniques: Methylation, Sequencing
Journal: Journal of Cellular and Molecular Medicine
Article Title: Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress
doi: 10.1111/jcmm.15231
Figure Lengend Snippet: mRNA expression of CAT , Gpx1 , Gpx4 , SOD1 , SOD2 and NOS1 in brain structures of animals exposed to chronic mild stress (CMS) for 2 wk (Control, Stressed) and in animals exposed to CMS for 7 wk and administered vehicle (1 mL/kg) or venlafaxine (10 mg/kg) for 5 wk (Control/Venla, Stressed/Saline, Stressed/Venla). Relative gene expression levels were estimated using a 2 −ΔCt (Ctgene–Ct18S) method. Data represent means ± SEM. N = 6. * P < .05; relative to Stressed/Saline group. # P < .05; relative to Control group
Article Snippet: Expression of SOD1 (assay ID: Rn00566938_m1), SOD2 (assay ID: Rn00690588_g1), Gpx1 (assay ID: Rn00577994_g1), Gpx4 (assay ID: Rn00820818_g1), CAT (assay ID: Rn00560930_m1), NOS1 (assay ID:
Techniques: Expressing
Journal: Journal of Cellular and Molecular Medicine
Article Title: Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress
doi: 10.1111/jcmm.15231
Figure Lengend Snippet: Differences in methylation level of CAT (A), Gpx4 promoter 2 (B), Gpx4 promoter 3 (C) and NOS1 promoter 3 (D) between brain tissue and PBMCs of animals exposed to chronic mild stress (CMS) for 2 wk (Control, Stressed) and in animals exposed to CMS for 7 wk and administered vehicle (1 mL/kg) or venlafaxine (10 mg/kg) for 5 weeks (Control/Venla, Stressed/Saline, Stressed/Venla). The methylation level of all four genes measured in hippocampus, amygdala, hypothalamus, midbrain, cortex and basal ganglia were pooled and compared with the data detected in PBMCs. Data represent median and maximum‐minimum values. N = 6. * P < .05, ** P < .01, *** P < .001
Article Snippet: Expression of SOD1 (assay ID: Rn00566938_m1), SOD2 (assay ID: Rn00690588_g1), Gpx1 (assay ID: Rn00577994_g1), Gpx4 (assay ID: Rn00820818_g1), CAT (assay ID: Rn00560930_m1), NOS1 (assay ID:
Techniques: Methylation
Journal: Journal of Cellular and Molecular Medicine
Article Title: Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress
doi: 10.1111/jcmm.15231
Figure Lengend Snippet: Differences in methylation level of CAT (A), Gpx1 (B), Gpx4 promoter 2 (C), Gpx4 promoter 3 (D), SOD1 (E), SOD2 (F), NOS1 promoter 3 (G) and NOS1 promoter 7 (H) between brain tissue and PBMCs of animals exposed to chronic mild stress (CMS) for 2 wk (Control, Stressed) and in animals exposed to CMS for 7 wk and administered vehicle (1 mL/kg) or venlafaxine (10 mg/kg) for 5 wk (Control/Venla, Stressed/Saline, Stressed/Venla). The methylation level of all eight genes measured in hippocampus, amygdala, hypothalamus, midbrain, cortex and basal ganglia were pooled and compared with the data detected in PBMCs. Data represent means ± SEM. N = 6. * P < .05, ** P < .01; relative to PBMCs
Article Snippet: Expression of SOD1 (assay ID: Rn00566938_m1), SOD2 (assay ID: Rn00690588_g1), Gpx1 (assay ID: Rn00577994_g1), Gpx4 (assay ID: Rn00820818_g1), CAT (assay ID: Rn00560930_m1), NOS1 (assay ID:
Techniques: Methylation