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Image Search Results
Journal: bioRxiv
Article Title: Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs
doi: 10.1101/2023.01.17.524372
Figure Lengend Snippet: (A) A549, LXF289, H1944, H1299, H23 and HCC827 cells were treated with NO scavenger cPTIO (50 µM), NO donor NOC-18 (40 µM), or a combination of both for 72 h. Growth rates were calculated based on nuclei count and presented as box plots (**** p <0.0001, ns , not significant, two-tailed unpaired t test using the original data). The results are representative of three independent experiments . (B) LXF289, A549, H1299 and H23 cells were treated with a series of concentrations of SOD1 inhibitor LCS-1 for 24 h in the presence of NOC-18 (200 µM). Cell viability was quantified by the CellTiter-Blue assay. Bars represent results from three technical replicates. The results are representative of two independent experiments.
Article Snippet: The next day (day 0), cells were treated with 50 µM NO scavenger cPTIO (Sigma), 40 µM NO
Techniques: Two Tailed Test, CtB Assay
Journal: bioRxiv
Article Title: Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs
doi: 10.1101/2023.01.17.524372
Figure Lengend Snippet: H23, H661 and HCC827 cells were treated with a concentration series of DKFZ-682 for 24 h in the presence of NO donor NOC-18 (200 µM), and the cell viability was quantified by the CellTiter-Blue assay. Data points represent results from three technical replicates. The results are representative of two independent experiments.
Article Snippet: The next day (day 0), cells were treated with 50 µM NO scavenger cPTIO (Sigma), 40 µM NO
Techniques: Concentration Assay, CtB Assay