Journal: Nanomedicine (London, England)

Article Title: The effects of carbon nanotubes on lung and dermal cellular behaviors

doi: 10.2217/nnm.14.42

Figure Lengend Snippet: Basis of carbon nanotube biological activities.

Article Snippet: MWCNT: short, L 1–2 μm; long, L 13 or 36 μm; tangle, L 1–5 or 5–20 μm , Nanostructured & Amorphous Materials, Inc. (TX, USA); NanoLab, Inc. (MA, USA); Mitsui & Co. , Met5A; THP-1 , 5–50 μg/cm 2 , 24 h , 0.5% BSA in RPMI media , IL-1β, TNF-α, IL-6, IL-8 , MWCNTs directly induced a length-dependent proinflammatory response from THP-1 cells, the effects of which can be amplified by cytokines from Met5A cells , [ 17 ].

Techniques: Saline, Membrane, Amplification, CCK-8 Assay, Modification, Dispersion, Cell Culture, Cell Counting, Activation Assay, Purification, Activity Assay, In Vitro, In Vivo, Solvent

Journal: Nanotoxicology

Article Title: Lung Deposition Patterns of MWCNT Vary With Degree of Carboxylation

doi: 10.1080/17435390.2018.1530392

Figure Lengend Snippet: Representative CytoViva hyperspectral dark-field photomicrographs (SFF) of Balb/c mouse lung sections exposed to various MWCNT for 7 days post-particle exposure. Bright green areas indicate MWCNT deposition. A) Dispersion media control for 7 days. B) The source MWCNT for 7 days with particle that appears to be isolated primarily in alveolar macrophages within the alveolar spaces of the lung section. C) Particle f-MWCNT38.4 (5 min) for 7 days that appears to be isolated exclusively in numerous alveolar macrophages in a lung airway. D) Particle f-MWCNT14.7 (120 min) for 7 days dispersing throughout the epithelial tissue matrix in addition to alveolar macrophage uptake. This particle deposition is not limited to particular lung areas, but freely disperses throughout the lung tissue. Magnification at 400x (40x objective) for all images and micrometer scale bar = 20 microns.

Article Snippet: CytoViva hyperspectral dark-field detection of MWCNT Due to the difficulties encountered in imaging small f-MWCNT in the high magnification bright field microscopy, an alternative method was used, which was designed for the specific application of ENM detection.

Techniques: Dispersion, Control, Isolation

Journal: Nanotoxicology

Article Title: Lung Deposition Patterns of MWCNT Vary With Degree of Carboxylation

doi: 10.1080/17435390.2018.1530392

Figure Lengend Snippet: Representative CytoViva hyperspectral dark-field photomicrographs (SFF) of Balb/c mouse lung sections exposed to various MWCNT for 28 days post-particle exposure. Bright green areas indicate MWCNT deposition. A) Dispersion media control for 28 days. B) The source MWCNT for 28 days C) Particle f-MWCNT38.4 (5 min) for 28 days. D) Particle f-MWCNT14.7 (120 min) for 28 days. Magnification at 400x (40x objective) for all images and micrometer scale bar = 20 microns.

Article Snippet: CytoViva hyperspectral dark-field detection of MWCNT Due to the difficulties encountered in imaging small f-MWCNT in the high magnification bright field microscopy, an alternative method was used, which was designed for the specific application of ENM detection.

Techniques: Dispersion, Control