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Image Search Results
Journal: Molecules
Article Title: A Structural Overview of Vascular Endothelial Growth Factors Pharmacological Ligands: From Macromolecules to Designed Peptidomimetics
doi: 10.3390/molecules26226759
Figure Lengend Snippet: Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.
Article Snippet: , Dual dAb , Similar to VEGFR-1 D2 , Mammalian cell-derived hVEGF 165 : K d = 3.27 pM; E. coli expressed hVEGF 165 : K d = 3.14 pM/T200 SPR hVEGF-A 165 : EC 50 = 32 ± 2.7 pM; hVEGF 121: EC 50 = 127
Techniques: Competitive Binding Assay, Binding Assay, Enzyme-linked Immunosorbent Assay, Labeling, Mutagenesis, Thermal Shift Assay