mouse mdc1 Search Results


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RayBiotech inc mouse ccl22 mdc1 elisa kit
Mouse Ccl22 Mdc1 Elisa Kit, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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OriGene mouse mdc1
Fig. 5. BRIT1 and <t>MDC1</t> could both contribute to the ATM–γ-H2AX axis of DSB resolution during CSR. (A) Representative flow cytometry of CSR to IgG1 in splenic B cells derived from Mb1-Cre control, BRIT1 KO, and AID KO mice treated with ATMi or with DMSO vehicle control. (B) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05). (C) Immunoblot analysis of whole- cell lysates from control, BRIT1 KO, or AID KO cells treated with ATMi or DMSO. (D) Immunoblot analysis of whole-cell lysates from control or BRIT1 KO cells transduced with two different MDC1 shRNAs (sh1 and sh2) or scrambled control. (E) Representative flow cytometry of CSR to IgG1 in splenic B cells of indicated genotypes expressing MDC1 knockdown shRNAs sh1 or sh2. (F) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05).
Mouse Mdc1, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Merck KGaA mouse monoclonal anti-mdc1 p2b11
Fig. 5. BRIT1 and <t>MDC1</t> could both contribute to the ATM–γ-H2AX axis of DSB resolution during CSR. (A) Representative flow cytometry of CSR to IgG1 in splenic B cells derived from Mb1-Cre control, BRIT1 KO, and AID KO mice treated with ATMi or with DMSO vehicle control. (B) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05). (C) Immunoblot analysis of whole- cell lysates from control, BRIT1 KO, or AID KO cells treated with ATMi or DMSO. (D) Immunoblot analysis of whole-cell lysates from control or BRIT1 KO cells transduced with two different MDC1 shRNAs (sh1 and sh2) or scrambled control. (E) Representative flow cytometry of CSR to IgG1 in splenic B cells of indicated genotypes expressing MDC1 knockdown shRNAs sh1 or sh2. (F) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05).
Mouse Monoclonal Anti Mdc1 P2b11, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+mdc1/mouse+monoclonal+anti+mdc1+p2b11/pm24333722-40-61-66
Average 90 stars, based on 1 article reviews
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Mdc1 Mouse 4 unique 29mer shRNA constructs in retroviral untagged vector
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Mdc1 untagged Mouse mediator of DNA damage checkpoint 1 Mdc1 10ug
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Mdc1 KN2 0 Mouse gene knockout kit via CRISPR non homology mediated
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qSTAR qPCR primer pairs against Mus musculus gene Mdc1
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Mdc1 Mouse shRNA lentiviral particles 4 unique 29mer target specific shRNA 1 scramble control 0 5 ml each 10 7 TU ml
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Mouse Monoclonal Anti MDC1 Antibody
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Fig. 5. BRIT1 and MDC1 could both contribute to the ATM–γ-H2AX axis of DSB resolution during CSR. (A) Representative flow cytometry of CSR to IgG1 in splenic B cells derived from Mb1-Cre control, BRIT1 KO, and AID KO mice treated with ATMi or with DMSO vehicle control. (B) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05). (C) Immunoblot analysis of whole- cell lysates from control, BRIT1 KO, or AID KO cells treated with ATMi or DMSO. (D) Immunoblot analysis of whole-cell lysates from control or BRIT1 KO cells transduced with two different MDC1 shRNAs (sh1 and sh2) or scrambled control. (E) Representative flow cytometry of CSR to IgG1 in splenic B cells of indicated genotypes expressing MDC1 knockdown shRNAs sh1 or sh2. (F) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05).

Journal: Proceedings of the National Academy of Sciences of the United States of America

Article Title: BRCT-domain protein BRIT1 influences class switch recombination.

doi: 10.1073/pnas.1708211114

Figure Lengend Snippet: Fig. 5. BRIT1 and MDC1 could both contribute to the ATM–γ-H2AX axis of DSB resolution during CSR. (A) Representative flow cytometry of CSR to IgG1 in splenic B cells derived from Mb1-Cre control, BRIT1 KO, and AID KO mice treated with ATMi or with DMSO vehicle control. (B) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05). (C) Immunoblot analysis of whole- cell lysates from control, BRIT1 KO, or AID KO cells treated with ATMi or DMSO. (D) Immunoblot analysis of whole-cell lysates from control or BRIT1 KO cells transduced with two different MDC1 shRNAs (sh1 and sh2) or scrambled control. (E) Representative flow cytometry of CSR to IgG1 in splenic B cells of indicated genotypes expressing MDC1 knockdown shRNAs sh1 or sh2. (F) Quantification of CSR to IgG1 (n = 3; **P < 0.005, *P < 0.05).

Article Snippet: The shRNAs (sh3 and sh4) against mouse MDC1 were obtained from Origene (TG517490).

Techniques: Flow Cytometry, Derivative Assay, Control, Western Blot, Transduction, Expressing, Knockdown