mifepristone Search Results


94
Tocris ru486
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MedChemExpress mifepristone mce
Mifepristone Mce, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Selleck Chemicals mifepristone ru486
Mifepristone Ru486, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MedChemExpress mif inhibitor
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steraloids inc mifepristone
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TargetMol p4
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86
LKT Laboratories ru486
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
Ru486, supplied by LKT Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Tocris mifepristone
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
Mifepristone, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology mifepristone
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
Mifepristone, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Toronto Research Chemicals n demethyl mifepristone d230950
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
N Demethyl Mifepristone D230950, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Thermo Fisher pa5
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
Pa5, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Hirschmann mifepristone
( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by <t>RU486</t> (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.
Mifepristone, supplied by Hirschmann, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by RU486 (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.

Journal: Scientific Reports

Article Title: Glucocorticoid affects dendritic transport of BDNF-containing vesicles

doi: 10.1038/srep12684

Figure Lengend Snippet: ( a ) DEX-induced enhancement of BDNF vesicle transport was blocked by RU486 (mifepristone, a GR antagonist). Data were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 302, 181, 258, and 196 vesicles, respectively. *** P < 0.001 for the difference between moving (antero-, retro-grade, and back & forth) vs. stationary vesicles, student’s t -test. ( b ) The proportion of stationary vesicles in each condition was summarized. *** P < 0.001, ** P < 0.01. Statistical significance was evaluated by two-way ANOVA followed by Bonferroni post-hoc test. ( c ) RU486 partially suppressed the increased velocity of BDNF vesicle transport after DEX treatment. Velocities were obtained from 8 (CON), 6 (DEX), 7 (RU), and 6 (DEX + RU) neurons from three independent culture preparations including 40 (CON), 37 (DEX), 23 (RU), and 20 (DEX + RU) vesicles. CON (median 0.45 μm/sec, percentiles 0.4–0.5); DEX (median 0.8 μm/sec, percentiles 0.6–1.1); RU (median 0.4 μm/sec, percentiles 0.4–0.6); DEX + RU (median 0.5 μm/sec, percentiles 0.4–0.88). Circles outside the whiskers indicate outliers. *** P < 0.001, ** P < 0.01, Kruskal-Wallis test.

Article Snippet: RU486 (Mifepristone, 1 μM, LKT Laboratories Inc., MN) was applied 20 min before starting DEX treatment.

Techniques:

( a ) DEX (1 and 10 μM, for 24 h) significantly increased Htt expression in cortical neurons. (n = 5). *P < 0.05 vs. CON, one-way ANOVA followed by Bonferroni post-hoc test. ( b ) Pretreatment with RU486 blocked the effect of DEX on Htt expression levels (n = 8). *** P < 0.001, ** P < 0.01, n.s. means not significantly different ( P > 0.05), two-way ANOVA followed by Bonferroni post-hoc test. Htt: huntingtin. The gels have been run under the same experimental condition in each experiment. Original blot images before cropping are shown in .

Journal: Scientific Reports

Article Title: Glucocorticoid affects dendritic transport of BDNF-containing vesicles

doi: 10.1038/srep12684

Figure Lengend Snippet: ( a ) DEX (1 and 10 μM, for 24 h) significantly increased Htt expression in cortical neurons. (n = 5). *P < 0.05 vs. CON, one-way ANOVA followed by Bonferroni post-hoc test. ( b ) Pretreatment with RU486 blocked the effect of DEX on Htt expression levels (n = 8). *** P < 0.001, ** P < 0.01, n.s. means not significantly different ( P > 0.05), two-way ANOVA followed by Bonferroni post-hoc test. Htt: huntingtin. The gels have been run under the same experimental condition in each experiment. Original blot images before cropping are shown in .

Article Snippet: RU486 (Mifepristone, 1 μM, LKT Laboratories Inc., MN) was applied 20 min before starting DEX treatment.

Techniques: Expressing