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Image Search Results
Journal: Frontiers in Cell and Developmental Biology
Article Title: (Multi-) omics studies of ILC2s in inflammation and metabolic diseases
doi: 10.3389/fcell.2024.1473616
Figure Lengend Snippet: ILC2 metabolism in healthy and diseased state (A) In healthy homeostatic state, ILC2s use glycolysis and FAO to fuel OXPHOS for the production of IL-5, IL-13 cytokines to maintain their survival. (B) Upon helminth infection in the lung, IL-33 is released which in turn activates ILC2s, leading to FAO and Arg1 activity for IL-13 production in order to enhance the anti-inflammatory and tissue-repair functions of ILC2s. (C) In metabolic disorders, impaired metabolism due to high glucose and free fatty acids (FFA), ILC2 metabolism is disrupted, partly leading to increased glycolysis to manage the excess of glucose Abbreviations: Arginase-1 (Arg1), Fatty acid oxidation (FAO), Free fatty acids (FFA), Innate lymphoid cells type 2 (ILC2s), Interleukin (IL), oxidative phosphorylation (OXPHOS). Made with biorender.com . The “?” indicates that there is a yet unknown mechanism.
Article Snippet:
Techniques: Infection, Activity Assay, Phospho-proteomics
Journal: Frontiers in Cell and Developmental Biology
Article Title: (Multi-) omics studies of ILC2s in inflammation and metabolic diseases
doi: 10.3389/fcell.2024.1473616
Figure Lengend Snippet: Overview of ILC2 focused omics approaches.
Article Snippet:
Techniques: DNA Methylation Assay, Modification, Biomarker Discovery, Quantitative Proteomics, Expressing, Protein-Protein interactions
Journal: Journal of Genetic Engineering & Biotechnology
Article Title: Correlation of methylation status in MTHFR promoter region with recurrent pregnancy loss
doi: 10.1186/s43141-021-00147-w
Figure Lengend Snippet: Roc curve analysis of methylation profile of gene-specific MTHFR. AUC, area under the curve; 95% CI, 95% confidence interval
Article Snippet: Our study is limited by the fact that we could not analyze fetal tissue as well; results would have been more valid and interesting after comparison of
Techniques: Methylation
Journal: Journal of Genetic Engineering & Biotechnology
Article Title: Correlation of methylation status in MTHFR promoter region with recurrent pregnancy loss
doi: 10.1186/s43141-021-00147-w
Figure Lengend Snippet: Methylation among cases of pregnancy loss compared to controls
Article Snippet: Our study is limited by the fact that we could not analyze fetal tissue as well; results would have been more valid and interesting after comparison of
Techniques: Methylation