kn-62 Search Results


cas 57265 65 3 kn 62 tocris  (Tocris)
93
Tocris cas 57265 65 3 kn 62 tocris
Cas 57265 65 3 Kn 62 Tocris, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pm33022213-255-250-253?v=Tocris
Average 93 stars, based on 1 article reviews
cas 57265 65 3 kn 62 tocris - by Bioz Stars, 2026-07
93/100 stars
  Buy from Supplier
kn 62  (Tocris)
95
Tocris kn 62
Kn 62, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc03204222-240-24-36?v=Tocris
Average 95 stars, based on 1 article reviews
kn 62 - by Bioz Stars, 2026-07
95/100 stars
  Buy from Supplier
kn 62  (Thermo Fisher)
86
Thermo Fisher kn 62
Kn 62, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/10__1074_slash_jbc__m112__413997-84-50-65?v=Thermo+Fisher
Average 86 stars, based on 1 article reviews
kn 62 - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier
pan camks inhibitor kn 62 s7422  (Selleck Chemicals)
93
Selleck Chemicals pan camks inhibitor kn 62 s7422
Pan Camks Inhibitor Kn 62 S7422, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pm40526468-877-1-8?v=Selleck+Chemicals
Average 93 stars, based on 1 article reviews
pan camks inhibitor kn 62 s7422 - by Bioz Stars, 2026-07
93/100 stars
  Buy from Supplier
kn62  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology kn62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn62, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc12564499-280-18-48?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
kn62 - by Bioz Stars, 2026-07
93/100 stars
  Buy from Supplier
camkii reagents kn-62  (LC Laboratories)
90
LC Laboratories camkii reagents kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Camkii Reagents Kn 62, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/10__1074_slash_jbc__m110__183558-58-1-4?v=LC+Laboratories
Average 90 stars, based on 1 article reviews
camkii reagents kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62 (biomol)  (Biomol GmbH)
90
Biomol GmbH kn-62 (biomol)
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62 (Biomol), supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc04228944-198-0-1?v=Biomol+GmbH
Average 90 stars, based on 1 article reviews
kn-62 (biomol) - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62  (Microm International GmbH)
90
Microm International GmbH kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62, supplied by Microm International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc01915779-10-38-13?v=Microm+International+GmbH
Average 90 stars, based on 1 article reviews
kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62  (Seikagaku corporation)
90
Seikagaku corporation kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62, supplied by Seikagaku corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/10__2170_slash_physiolsci__rp014507-40-11-12?v=Seikagaku+corporation
Average 90 stars, based on 1 article reviews
kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62  (Cayman Chemical)
90
Cayman Chemical kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc05547630-346-16-29?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62  (Enzo Biochem)
90
Enzo Biochem kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pmc04434927-128-12-19?v=Enzo+Biochem
Average 90 stars, based on 1 article reviews
kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
kn-62  (Biaffin Inc)
90
Biaffin Inc kn-62
Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor <t>KN62</t> (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.
Kn 62, supplied by Biaffin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/kn-62/pm25380824-202-42-43?v=Biaffin+Inc
Average 90 stars, based on 1 article reviews
kn-62 - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier

Image Search Results


Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor KN62 (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.

Journal: International Journal of Molecular Sciences

Article Title: The Cannabinoid CB 1 Receptor Inverse Agonist/Antagonist SR141716A Activates the Adenylate Cyclase/PKA Signaling Pathway Among Other Intracellular Emetic Signals to Evoke Vomiting in Least Shrews ( Cryptotis parva )

doi: 10.3390/ijms26209884

Figure Lengend Snippet: Effects of modulators of cell membrane Ca 2+ channels on CB 1 receptor inverse agonist/antagonist SR141716A (20 mg/kg, i.p.)-induced vomiting. Different groups of least shrews were given an injection of either the corresponding vehicle or varying doses of one of the following: (1) CaMKII inhibitor KN62 (i.p.); (2) the L-type Ca 2+ channel (LTCC) inhibitors nifedipine (s.c.) and amlodipine (i.p.); (3) store-operated Ca 2+ entry blockers YM 58483 (i.p.) and MRS 1845 (i.p.); and (4) the TRPV1R agonist resiniferatoxin (RTX) (s.c.), 30 min prior to SR141716A (20 mg/kg, i.p.) injection. Emetic parameters were recorded for the next 30 min. The frequency of emesis ( A , C , E , G , I , K ) was analyzed using Kruskal–Wallis non-parametric one-way ANOVA followed by Dunn’s post hoc test and presented as mean ± SEM. The percentage of shrews vomiting ( B , D , F , H , J , L ) was analyzed using the chi-square test and presented as mean. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. 0 mg/kg. The number of animals in each group is presented at the top of the corresponding column.

Article Snippet: The following drugs were used for the present studies: SR141716A, H-89, U0126, PD98059, AR-A014418, SB216763, LY294002, U73122, GF109203X, KN62, amlodipine, YM-58483, MRS-1845, and RTX were purchased from Tocris (Minneapolis, MN, USA); nifedipine and sulpiride were purchased from Sigma-Aldrich (St. Louis, MO, USA); dantrolene and 2-APB were purchased from Santa Cruz Biotechnology (Dallas, TX, USA); and palonosetron was kindly provided by Helsinn Health Care (Lugano, Switzerland).

Techniques: Membrane, Injection