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Image Search Results
Journal: Brain Pathology
Article Title: MIF Receptor CD 74 is Restricted to Microglia/Macrophages, Associated with a M 1‐Polarized Immune Milieu and Prolonged Patient Survival in Gliomas
doi: 10.1111/bpa.12194
Figure Lengend Snippet: CD74 expression is differentially regulated in astrocytic tumors and normal central nervous system (CNS) tissues. Box and Whisker plots for CD74‐positive cells (in %) in astrocytomas I–IV, GBM infiltration zones as well as normal‐appearing CNS tissues are depicted. The relative amount of CD74‐positive cells in pilocytic astrocytoma, World Health Organization (WHO) grade I (n = 47); diffuse astrocytoma WHO grade II (n = 16); anaplastic astrocytoma WHO grade III (n = 35); glioblastoma WHO grade IV (n = 252), GBM infiltration zone (n = 37), normal‐appearing white matter of GBM samples (NAWM; n = 16) as well as normal‐appearing grey matter of GBM samples (NAGM; n = 44) was statistically assessed using the nonparametric Wilcoxon's test. A significance level of alpha = 0.05 was chosen for all testings. For adjustment of the P‐values because of multiple testing we used the method of Bonferroni–Holm. Statistical analysis was performed using JMP 8.0.1 software (SAS).
Article Snippet: Statistical analysis was performed using
Techniques: Expressing, Whisker Assay, Software