Journal: Veterinary Research

Article Title: The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori

doi: 10.1186/1297-9716-43-75

Figure Lengend Snippet: Number of colonizing H. suis bacteria. Shown is the average number of H. suis bacteria/milligram tissue in the stomach of BALB/c and C57BL/6 mice 59 days after experimental infection.

Article Snippet: Seven-week-old, female specific-pathogen-free BALB/c and C57BL/6 mice, free of Helicobacter spp., were purchased from Harlan NL (Horst, The Netherlands).

Techniques: Bacteria, Infection

Journal: Veterinary Research

Article Title: The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori

doi: 10.1186/1297-9716-43-75

Figure Lengend Snippet: General cytokine expression profile after experimental H. suis infection in BALB/c and C57BL/6 mice. Shown are the mean fold changes in mRNA expression of indicated cytokines in H. suis -infected BALB/c and C57BL/6 mice. The mean fold change in the relevant uninfected control groups is equal to 1. An * indicates a statistically significant difference compared to uninfected control mice ( p < 0.05).

Article Snippet: Seven-week-old, female specific-pathogen-free BALB/c and C57BL/6 mice, free of Helicobacter spp., were purchased from Harlan NL (Horst, The Netherlands).

Techniques: Expressing, Infection, Control

Journal: Veterinary Research

Article Title: The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori

doi: 10.1186/1297-9716-43-75

Figure Lengend Snippet: Cytokine expression profiles for each group of animals infected with H. suis strains HS1-9 and H. pylori strains SS1 or pMSS1. Shown are the mean fold changes of mRNA expression in HS1-HS9- and SS1- or pMSS1-infected BALB/c and C57BL/6 mice for IL-1β ( A ), IL-4 ( B ), IL-6 ( C ), IL-10 ( D ) and IL-17 ( E ). The mean fold change in the relevant uninfected control groups is equal to 1. An * indicates a significant upregulation of mRNA expression compared to uninfected control mice ( p < 0.05). An ** indicates a significant upregulation of mRNA expression compared to uninfected control mice ( p < 0.0056, i.e. the new cut-off p value obtained after Bonferroni correction for multiple comparisons).

Article Snippet: Seven-week-old, female specific-pathogen-free BALB/c and C57BL/6 mice, free of Helicobacter spp., were purchased from Harlan NL (Horst, The Netherlands).

Techniques: Expressing, Infection, Control

Journal: Veterinary Research

Article Title: The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori

doi: 10.1186/1297-9716-43-75

Figure Lengend Snippet: Correlation between cytokine expression and H. suis colonization. Shown are the correlation analyses between IL-6 ( A ), IL-17 ( B ), MIP-2 ( C ), IL-1β ( D ) and IL-10 ( E ) mRNA expression levels and the number of colonizing H. suis bacteria in stomachs of indicated mouse strains (BALB/c and C57BL/6). Correlation was measured by Spearman’s Rho (ρ).

Article Snippet: Seven-week-old, female specific-pathogen-free BALB/c and C57BL/6 mice, free of Helicobacter spp., were purchased from Harlan NL (Horst, The Netherlands).

Techniques: Expressing, Bacteria