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Image Search Results
Journal: bioRxiv
Article Title: Altered metabolic function induced by amyloid-beta oligomers and PSEN1-mutations in iPSC-derived astrocytes
doi: 10.1101/2023.08.23.554346
Figure Lengend Snippet: A) Heatmap displaying differential compounds identified using metabolomic analysis. Summary of Pathway analysis for the comparison of control and B) A246E, C) L286V and D) R278 fAD patient derived astrocytes. The pathway analysis results of PSEN1 astrocytes compared with control: the colour graduated from white to and red indicates the degree of significance, the size of bubble represents the number of metabolites hit in the pathway. E) Bar charts indicating intensity changes in key metabolites represented within metabolic pathway that were detected in astrocytes carrying PSEN1 mutations. Data shown is expressed as ± SD, n=6.
Article Snippet: Healthy control (ax0018) and PSEN1 human neural precursor cells (hNPCs) carrying
Techniques: Comparison, Control, Derivative Assay