indoximod Search Results


indoximod  (MedChemExpress)
94
MedChemExpress indoximod
Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of <t>Indoximod</t> (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.
Indoximod, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/Indoximod/pmc07815474-35-0-4
Average 94 stars, based on 1 article reviews
indoximod - by Bioz Stars, 2026-10
94/100 stars
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indoximod  (Selleck Chemicals)
93
Selleck Chemicals indoximod
Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of <t>Indoximod</t> (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.
Indoximod, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/Indoximod+(NLG-8189%EF%BC%89/pm37717018-251-0-2
Average 93 stars, based on 1 article reviews
indoximod - by Bioz Stars, 2026-10
93/100 stars
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n fmoc 1 methyltryptophan  (Chem Impex International)
95
Chem Impex International n fmoc 1 methyltryptophan
Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of <t>Indoximod</t> (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.
N Fmoc 1 Methyltryptophan, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/1-Methyl-L-tryptophan/pm37976523__cb3c00553_si_005-89-21-23
Average 95 stars, based on 1 article reviews
n fmoc 1 methyltryptophan - by Bioz Stars, 2026-10
95/100 stars
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d-1mt  (NewLink Genetics)
90
NewLink Genetics d-1mt
Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of <t>Indoximod</t> (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.
D 1mt, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod+nlg+8189/pmc03556270-45-0-6
Average 90 stars, based on 1 article reviews
d-1mt - by Bioz Stars, 2026-10
90/100 stars
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indoximod  (NewLink Genetics)
90
NewLink Genetics indoximod
Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of <t>Indoximod</t> (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.
Indoximod, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod/us11596666-1210-53-56
Average 90 stars, based on 1 article reviews
indoximod - by Bioz Stars, 2026-10
90/100 stars
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indoximod ido inhibitor  (NewLink Genetics)
90
NewLink Genetics indoximod ido inhibitor
A list of the different GBM therapies, associated drug names, companies in charge of their development or commercialization, as well as drug proposed mode of action.
Indoximod Ido Inhibitor, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/ido+inhibitor+indoximod/pmc06147115-21-2-5
Average 90 stars, based on 1 article reviews
indoximod ido inhibitor - by Bioz Stars, 2026-10
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nlg8189, known 1-methyl- d -tryptophan (1-mt  (Lumos Pharma)
90
Lumos Pharma nlg8189, known 1-methyl- d -tryptophan (1-mt
A list of the different GBM therapies, associated drug names, companies in charge of their development or commercialization, as well as drug proposed mode of action.
Nlg8189, Known 1 Methyl D Tryptophan (1 Mt, supplied by Lumos Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod/pmc11770058-148-10-24
Average 90 stars, based on 1 article reviews
nlg8189, known 1-methyl- d -tryptophan (1-mt - by Bioz Stars, 2026-10
90/100 stars
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indoximod hard gelatin capsules  (NewLink Genetics)
90
NewLink Genetics indoximod hard gelatin capsules
Square symbols represent patients enrolled at a once-daily <t>indoximod</t> dose level and circles represent patients enrolled at a twice-daily dose level. Blue shapes represent nonresponders and red shapes represent responders to subsequent chemotherapy. Black shapes represent patients who did not get therapy post vaccine or whose response is unknown.
Indoximod Hard Gelatin Capsules, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod+hard+gelatin+capsules/pmc05839376-148-0-19
Average 90 stars, based on 1 article reviews
indoximod hard gelatin capsules - by Bioz Stars, 2026-10
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small molecule ido inhibitor indoximod  (NewLink Genetics)
90
NewLink Genetics small molecule ido inhibitor indoximod
Square symbols represent patients enrolled at a once-daily <t>indoximod</t> dose level and circles represent patients enrolled at a twice-daily dose level. Blue shapes represent nonresponders and red shapes represent responders to subsequent chemotherapy. Black shapes represent patients who did not get therapy post vaccine or whose response is unknown.
Small Molecule Ido Inhibitor Indoximod, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/small+molecule+ido+inhibitor+indoximod/us11813280-40-5-6
Average 90 stars, based on 1 article reviews
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90/100 stars
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indoximod 23 b  (NewLink Genetics)
90
NewLink Genetics indoximod 23 b
The IDO inhibitors epacadostat ( 21 ), EOS‐200271 ( 22 ), navoximod ( 23 a ) and <t>indoximod</t> ( 23 b ), and BMS‐986205 ( 24 ).
Indoximod 23 B, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod+23+b/pmc05900885-170-5-0
Average 90 stars, based on 1 article reviews
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indoximod (nlg0401)  (NewLink Genetics)
90
NewLink Genetics indoximod (nlg0401)
Selected immune checkpoint inhibitors in clinical trials.
Indoximod (Nlg0401), supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod++nlg0401+/pmc06144513-68-1-5
Average 90 stars, based on 1 article reviews
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indoximod for the treatment of breast, brain, melanoma and pancreatic cancer  (NewLink Genetics)
90
NewLink Genetics indoximod for the treatment of breast, brain, melanoma and pancreatic cancer
Selected immune checkpoint inhibitors in clinical trials.
Indoximod For The Treatment Of Breast, Brain, Melanoma And Pancreatic Cancer, supplied by NewLink Genetics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/indoximod/indoximod+for+the+treatment+of+breast++brain++melanoma+and+pancreatic+cancer/pm25503330-12-69-59
Average 90 stars, based on 1 article reviews
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Image Search Results


Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of Indoximod (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.

Journal: Bioactive Materials

Article Title: Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy

doi: 10.1016/j.bioactmat.2020.12.023

Figure Lengend Snippet: Scheme and characterization of aPD/IND@MON-aANN nanomedicine. (a)Schematic illustration of aPD/IND@MON-aANN synthesis, ANXA1 antibody-activated trans -endothelial transcytosis to augment nanomedicine extravasation and the efficacy of cancer immunotherapy by synergistic modulation of the tumor microenvironment. (b)The zeta potential of MON, MON-NH 2 and MON-COOH measured by DLS. (c) The hydrodynamic size of MON-COOH, MON-aANN and MON-PEG-aANN measured by DLS. (d) Fluorescence emission spectra of aPD@MON-aANN with FITC- labelled MON, PE-labelled aPD-L1 and IRDye 680RD-labelled aANXA1. (e) Representative TEM image of aPD/IND@MON-aANN nanoparticles. Scale bar = 50 nm. (f,g) The release profile of Indoximod (f) and aPD-L1 (g) of aPD/IND@MON-aANN examined in pure SBF or SBF with 10 mM GSH in 48 h.

Article Snippet: Indoximod were purchased from MCE.

Techniques: Zeta Potential Analyzer, Fluorescence

A list of the different GBM therapies, associated drug names, companies in charge of their development or commercialization, as well as drug proposed mode of action.

Journal: Frontiers in Pharmacology

Article Title: Glioblastoma Treatments: An Account of Recent Industrial Developments

doi: 10.3389/fphar.2018.00879

Figure Lengend Snippet: A list of the different GBM therapies, associated drug names, companies in charge of their development or commercialization, as well as drug proposed mode of action.

Article Snippet: Indoximod , IDO inhibitor , Newlinkgenetics , Inhibits IDO (indoleamine 2,3-dioxygenase) that inactivates NK (natural killer) cells and generates Tregs (regulatory T cells)..

Techniques: Activity Assay, Binding Assay, Modification, Activation Assay, Injection, Amplification, Generated, Blocking Assay, Virus, Purification, Membrane, Transformation Assay, Saline

Square symbols represent patients enrolled at a once-daily indoximod dose level and circles represent patients enrolled at a twice-daily dose level. Blue shapes represent nonresponders and red shapes represent responders to subsequent chemotherapy. Black shapes represent patients who did not get therapy post vaccine or whose response is unknown.

Journal: Oncotarget

Article Title: A phase-1/2 study of adenovirus-p53 transduced dendritic cell vaccine in combination with indoximod in metastatic solid tumors and invasive breast cancer

doi: 10.18632/oncotarget.24118

Figure Lengend Snippet: Square symbols represent patients enrolled at a once-daily indoximod dose level and circles represent patients enrolled at a twice-daily dose level. Blue shapes represent nonresponders and red shapes represent responders to subsequent chemotherapy. Black shapes represent patients who did not get therapy post vaccine or whose response is unknown.

Article Snippet: Indoximod (50 mg and 200 mg hard gelatin capsules) was supplied by the National Cancer Institute’s Pharmacy Branch and NewLink Genetics.

Techniques:

The IDO inhibitors epacadostat ( 21 ), EOS‐200271 ( 22 ), navoximod ( 23 a ) and indoximod ( 23 b ), and BMS‐986205 ( 24 ).

Journal: Angewandte Chemie (International Ed. in English)

Article Title: Small Molecules Drive Big Improvements in Immuno‐Oncology Therapies

doi: 10.1002/anie.201707816

Figure Lengend Snippet: The IDO inhibitors epacadostat ( 21 ), EOS‐200271 ( 22 ), navoximod ( 23 a ) and indoximod ( 23 b ), and BMS‐986205 ( 24 ).

Article Snippet: NewLink Genetics is also investigating indoximod ( 23 b ), which is a direct inhibitor of neither IDO nor TDO at relevant pharmaceutical concentrations.

Techniques:

Selected immune checkpoint inhibitors in clinical trials.

Journal: Therapeutic Advances in Respiratory Disease

Article Title: New strategies in immunotherapy for lung cancer: beyond PD-1/PD-L1

doi: 10.1177/1753466618794133

Figure Lengend Snippet: Selected immune checkpoint inhibitors in clinical trials.

Article Snippet: , Indoximod (NLG0401) (IDOi) , NewLink Genetics Corp , Indoximod combination with docetaxel, tergenpumatucel-L , NSCLC, at least one prior platinum-doublet chemotherapy , NCT02460367 , Phase I/II Unknown.

Techniques: Recombinant