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Philips Healthcare
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Taxon Biosciences
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Chemagnetics Inc
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Verlag GmbH
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INCF
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INCF
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WuXi AppTec
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Corning Life Sciences
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INCF
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Image Search Results
Journal: Antimicrobial Agents and Chemotherapy
Article Title: Preclinical Evaluation of Amphihevir, a First-in-Class Clinical Hepatitis C Virus NS4B Inhibitor
doi: 10.1128/AAC.01237-19
Figure Lengend Snippet: Inhibition of HCV replicons after a 9-day continuous treatment. Amphihevir (YS_YD_0250) was used to treat stable HCV GT1b replicon cells for 9 days. The cells were passaged every 3 days, and medium was replaced with fresh medium containing the corresponding concentration of compounds. Cells were collected for cellular RNA extraction, and the RNA was then used to determine the inhibitory activity of the compound against HCV replicons. The amounts of HCV replicon RNA were determined by qRT-PCR.
Article Snippet: The
Techniques: Inhibition, Concentration Assay, RNA Extraction, Activity Assay, Quantitative RT-PCR
Journal: Antimicrobial Agents and Chemotherapy
Article Title: Preclinical Evaluation of Amphihevir, a First-in-Class Clinical Hepatitis C Virus NS4B Inhibitor
doi: 10.1128/AAC.01237-19
Figure Lengend Snippet: Inhibition of drug-resistant HCV replicons by the combination of amphihevir and fopitasvir. Stable HCV GT1b replicon cells were treated with amphihevir or fopitasvir alone or in combination for 21 days in the presence of G418. Replicon cell colonies are indicated by crystal violet staining.
Article Snippet: The
Techniques: Inhibition, Staining