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Image Search Results
Journal: Cold Spring Harbor Perspectives in Medicine
Article Title: Adaptive Immunity to Fungi
doi: 10.1101/cshperspect.a019612
Figure Lengend Snippet: Functions of different subclasses of immunoglobulins in mycoses. On encountering fungal pathogens, B cells undergo clonal expansion and antibody class switching. Depicted below are the five major classes of immunoglobulins secreted by B cells, namely, IgG, IgM, IgA, IgE, and IgD. Whereas specific roles of the former three have been reported in fungal diseases, the impact of IgE in this setting remains unclear. IgD has the ability to bind to outer surfaces of certain bacterial pathogens in the respiratory mucosa (Chen et al. 2009); however, its importance in fungal infections has not been studied.
Article Snippet: Additionally, pneumocystosis was reported in a patient with hypergammaglobulinemia who displayed inability to class switch from IgM to a more specific IgG subclass (
Techniques: