idt307 Search Results


94
MedChemExpress uptake reaction
Uptake Reaction, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/idt307/IDT307/pm42154662-427-1-16
Average 94 stars, based on 1 article reviews
uptake reaction - by Bioz Stars, 2026-09
94/100 stars
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N/A
IDT307 (Cat No.: I012823) is a fluorescent dye derivative of rhodamine used as a substrate for vesicular monoamine transporters (VMATs), particularly VMAT2. It is taken up into synaptic vesicles in a transporter-dependent manner, allowing researchers
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90
MatTek idt307
(a,b) Representative trajectories collected over 60 s of QD-bound DAT and DAT Val559 coding variants superimposed to the <t>IDT307</t> channel (scale bar = 5 μm). (c,d) Images at 4× magnification of images in a and b, respectively. (e) Cumulative frequency distributions of diffusion coefficients (D1–3) of immobile QDs, DAT Ala559, and DAT Val559 (Kolmogorov–Smirnov 2-sample test, p < 0.0001). (f) Averaged mean square displacement (MSD) plots (mean ± S.E.M.) and diffusion coefficient box plots (median, 25% and 75% interquartiles, one-way ANOVA followed by Bonferroni’s multiple comparison test, ***p < 0.001, ####p < 0.001 comparing data sets to immobilized QDs as control) of trajectories analyzed for DAT Ala559 and DAT Val559. (g) A 5 s displacement bar graph (mean ± S.E.M., unpaired Student’s t test, ***p < 0.001) and polar plots (outer radius limit = 2 μm) of single DAT Ala559 (gray) and DAT Val559 (blue). DAT displacements are normalized to their spatial origin. N (trajectories) are provided in Table S1.
Idt307, supplied by MatTek, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/idt307/idt307/pmc06411462-202-3-8
Average 90 stars, based on 1 article reviews
idt307 - by Bioz Stars, 2026-09
90/100 stars
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N/A
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+).In VitroIDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical
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Image Search Results


(a,b) Representative trajectories collected over 60 s of QD-bound DAT and DAT Val559 coding variants superimposed to the IDT307 channel (scale bar = 5 μm). (c,d) Images at 4× magnification of images in a and b, respectively. (e) Cumulative frequency distributions of diffusion coefficients (D1–3) of immobile QDs, DAT Ala559, and DAT Val559 (Kolmogorov–Smirnov 2-sample test, p < 0.0001). (f) Averaged mean square displacement (MSD) plots (mean ± S.E.M.) and diffusion coefficient box plots (median, 25% and 75% interquartiles, one-way ANOVA followed by Bonferroni’s multiple comparison test, ***p < 0.001, ####p < 0.001 comparing data sets to immobilized QDs as control) of trajectories analyzed for DAT Ala559 and DAT Val559. (g) A 5 s displacement bar graph (mean ± S.E.M., unpaired Student’s t test, ***p < 0.001) and polar plots (outer radius limit = 2 μm) of single DAT Ala559 (gray) and DAT Val559 (blue). DAT displacements are normalized to their spatial origin. N (trajectories) are provided in Table S1.

Journal: ACS chemical neuroscience

Article Title: Single quantum dot imaging reveals PKCβ-dependent alterations in membrane diffusion and clustering of an ADHD/autism/bipolar disorder-associated dopamine transporter variant

doi: 10.1021/acschemneuro.8b00350

Figure Lengend Snippet: (a,b) Representative trajectories collected over 60 s of QD-bound DAT and DAT Val559 coding variants superimposed to the IDT307 channel (scale bar = 5 μm). (c,d) Images at 4× magnification of images in a and b, respectively. (e) Cumulative frequency distributions of diffusion coefficients (D1–3) of immobile QDs, DAT Ala559, and DAT Val559 (Kolmogorov–Smirnov 2-sample test, p < 0.0001). (f) Averaged mean square displacement (MSD) plots (mean ± S.E.M.) and diffusion coefficient box plots (median, 25% and 75% interquartiles, one-way ANOVA followed by Bonferroni’s multiple comparison test, ***p < 0.001, ####p < 0.001 comparing data sets to immobilized QDs as control) of trajectories analyzed for DAT Ala559 and DAT Val559. (g) A 5 s displacement bar graph (mean ± S.E.M., unpaired Student’s t test, ***p < 0.001) and polar plots (outer radius limit = 2 μm) of single DAT Ala559 (gray) and DAT Val559 (blue). DAT displacements are normalized to their spatial origin. N (trajectories) are provided in Table S1.

Article Snippet: At the microscope, IDT307 was added to the MatTek dish prior to imaging.

Techniques: Diffusion-based Assay, Comparison, Control