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hvegf 165  (Meso Scale Diagnostics LLC)
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Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.
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Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.
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hvegf165  (GenScript corporation)
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Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.
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Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.

Journal: Molecules

Article Title: A Structural Overview of Vascular Endothelial Growth Factors Pharmacological Ligands: From Macromolecules to Designed Peptidomimetics

doi: 10.3390/molecules26226759

Figure Lengend Snippet: Structural and affinity data for VEGF ligands for which a co-structure with the growth factor has been published.

Article Snippet: , Dual dAb , Similar to VEGFR-1 D2 , Mammalian cell-derived hVEGF 165 : K d = 3.27 pM; E. coli expressed hVEGF 165 : K d = 3.14 pM/T200 SPR hVEGF-A 165 : EC 50 = 32 ± 2.7 pM; hVEGF 121: EC 50 = 127 ± 22.1 pM; mVEGF 164: EC 50 = 36 ± 4.7 pM/Mesoscale discovery binding assay VEGFR-1 IC 50 = 59 ± 11.8 pM;VEGFR-2 IC 50 = 22 ± 2.7 pM/receptor binding assay by Mesoscale discovery , V K ·dAb: 5FV1 V H dAb: 5FV2 [ ] .

Techniques: Competitive Binding Assay, Binding Assay, Enzyme-linked Immunosorbent Assay, Labeling, Mutagenesis, Thermal Shift Assay