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Image Search Results
Journal: Saudi Pharmaceutical Journal : SPJ
Article Title: Design, synthesis, molecular docking, and in vitro studies of 2-mercaptoquinazolin-4(3 H )-ones as potential anti-breast cancer agents
doi: 10.1016/j.jsps.2024.101971
Figure Lengend Snippet: Inhibition assay of the synthesized quinazolinone compounds (3a, 3b, 3e, 3 g, and 3 h) against KSP (% inhibition at 2 µM and IC 50 ), using Ispinesib as positive control, and against PI3Kδ using Idelalisib as positive control.
Article Snippet: The in vitro KSP ATPase inhibition assay of the selected five compounds (3a, 3b, 3e, 3 g and 3 h) having good glide XP score, was performed by the
Techniques: Inhibition, Synthesized, Positive Control, Control, Activity Assay