htmprss2 Search Results


vero-htmprss2 cells  (JCRB Cell Bank)
90
JCRB Cell Bank vero-htmprss2 cells
Vero Htmprss2 Cells, supplied by JCRB Cell Bank, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/vero-htmprss2 cells/product/JCRB Cell Bank
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vero-htmprss2 cells - by Bioz Stars, 2026-05
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dki mice (hace2 and htmprss2)  (Synbal Inc)
90
Synbal Inc dki mice (hace2 and htmprss2)
Functionality of hFcRn <t>in</t> <t>hACE2-TMPRSS2-FCGRT</t> TKI mice . (a) Pharmacokinetics of 1C3-YTE mAb, 1C3-WT mAb, and polyclonal human IgG (pAb) in TKI and <t>DKI</t> mice. Groups of treatment-naïve mice were injected intraperitoneally with 1 mg/kg mAbs or pAbs and bled at 3, 24, 72, 168, 336, and 504 h post-dose. Each mouse was bled at a maximum of two time points. Data are presented as the mean ± SEM of 3–8 mice/group/time point, pooled from two independent experiments. Group means at day 21 were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (b) Half-life of 1C3-YTE, 1C3-WT, and pAbs in TKI and DKI mice. Group means were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (c) Experimental protocol for the data shown in (d and e). TKI and DKI mice were injected intraperitoneally (d) or intranasally (e) with 0.5 mg/kg of 1C3-YTE, 1C3-WT, or an anti-SARS-CoV-1 hIgG (negative control). One day later, mice were inoculated intranasally with Omicron BA.2 (10 4 PFU in 30 μl) and nasal turbinate (nt) and lungs were harvested on day 2 post-infection. (d) and (e) RT-qPCR analysis of Omicron BA.2 subgenomic (sg) RNA and plaque assay of infectious virus in the nt and/or lungs of TKI and DKI mice on day 2 post-infection. Data are presented as the mean ± SEM of 6–12 mice/group, pooled from two independent experiments. Circles represent individual mice and dotted lines indicate the limit of detection. Group means were compared by the Kruskal–Wallis and Dunn's multiple comparisons tests. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001.
Dki Mice (Hace2 And Htmprss2), supplied by Synbal Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dki mice (hace2 and htmprss2)/product/Synbal Inc
Average 90 stars, based on 1 article reviews
dki mice (hace2 and htmprss2) - by Bioz Stars, 2026-05
90/100 stars
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vero e6 cells expressing htmprss2  (Makoto USA Inc)
90
Makoto USA Inc vero e6 cells expressing htmprss2
Functionality of hFcRn <t>in</t> <t>hACE2-TMPRSS2-FCGRT</t> TKI mice . (a) Pharmacokinetics of 1C3-YTE mAb, 1C3-WT mAb, and polyclonal human IgG (pAb) in TKI and <t>DKI</t> mice. Groups of treatment-naïve mice were injected intraperitoneally with 1 mg/kg mAbs or pAbs and bled at 3, 24, 72, 168, 336, and 504 h post-dose. Each mouse was bled at a maximum of two time points. Data are presented as the mean ± SEM of 3–8 mice/group/time point, pooled from two independent experiments. Group means at day 21 were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (b) Half-life of 1C3-YTE, 1C3-WT, and pAbs in TKI and DKI mice. Group means were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (c) Experimental protocol for the data shown in (d and e). TKI and DKI mice were injected intraperitoneally (d) or intranasally (e) with 0.5 mg/kg of 1C3-YTE, 1C3-WT, or an anti-SARS-CoV-1 hIgG (negative control). One day later, mice were inoculated intranasally with Omicron BA.2 (10 4 PFU in 30 μl) and nasal turbinate (nt) and lungs were harvested on day 2 post-infection. (d) and (e) RT-qPCR analysis of Omicron BA.2 subgenomic (sg) RNA and plaque assay of infectious virus in the nt and/or lungs of TKI and DKI mice on day 2 post-infection. Data are presented as the mean ± SEM of 6–12 mice/group, pooled from two independent experiments. Circles represent individual mice and dotted lines indicate the limit of detection. Group means were compared by the Kruskal–Wallis and Dunn's multiple comparisons tests. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001.
Vero E6 Cells Expressing Htmprss2, supplied by Makoto USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/vero e6 cells expressing htmprss2/product/Makoto USA Inc
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vero e6 cells expressing htmprss2  (Takeda)
86
Takeda vero e6 cells expressing htmprss2
Functionality of hFcRn <t>in</t> <t>hACE2-TMPRSS2-FCGRT</t> TKI mice . (a) Pharmacokinetics of 1C3-YTE mAb, 1C3-WT mAb, and polyclonal human IgG (pAb) in TKI and <t>DKI</t> mice. Groups of treatment-naïve mice were injected intraperitoneally with 1 mg/kg mAbs or pAbs and bled at 3, 24, 72, 168, 336, and 504 h post-dose. Each mouse was bled at a maximum of two time points. Data are presented as the mean ± SEM of 3–8 mice/group/time point, pooled from two independent experiments. Group means at day 21 were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (b) Half-life of 1C3-YTE, 1C3-WT, and pAbs in TKI and DKI mice. Group means were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (c) Experimental protocol for the data shown in (d and e). TKI and DKI mice were injected intraperitoneally (d) or intranasally (e) with 0.5 mg/kg of 1C3-YTE, 1C3-WT, or an anti-SARS-CoV-1 hIgG (negative control). One day later, mice were inoculated intranasally with Omicron BA.2 (10 4 PFU in 30 μl) and nasal turbinate (nt) and lungs were harvested on day 2 post-infection. (d) and (e) RT-qPCR analysis of Omicron BA.2 subgenomic (sg) RNA and plaque assay of infectious virus in the nt and/or lungs of TKI and DKI mice on day 2 post-infection. Data are presented as the mean ± SEM of 6–12 mice/group, pooled from two independent experiments. Circles represent individual mice and dotted lines indicate the limit of detection. Group means were compared by the Kruskal–Wallis and Dunn's multiple comparisons tests. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001.
Vero E6 Cells Expressing Htmprss2, supplied by Takeda, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/vero e6 cells expressing htmprss2/product/Takeda
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vero e6 cells expressing htmprss2 - by Bioz Stars, 2026-05
86/100 stars
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scicho hace2 tmprss2 cell line scicho hace2 htmprss2  (CLS Cell Lines Service GmbH)
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Functionality of hFcRn in hACE2-TMPRSS2-FCGRT TKI mice . (a) Pharmacokinetics of 1C3-YTE mAb, 1C3-WT mAb, and polyclonal human IgG (pAb) in TKI and DKI mice. Groups of treatment-naïve mice were injected intraperitoneally with 1 mg/kg mAbs or pAbs and bled at 3, 24, 72, 168, 336, and 504 h post-dose. Each mouse was bled at a maximum of two time points. Data are presented as the mean ± SEM of 3–8 mice/group/time point, pooled from two independent experiments. Group means at day 21 were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (b) Half-life of 1C3-YTE, 1C3-WT, and pAbs in TKI and DKI mice. Group means were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (c) Experimental protocol for the data shown in (d and e). TKI and DKI mice were injected intraperitoneally (d) or intranasally (e) with 0.5 mg/kg of 1C3-YTE, 1C3-WT, or an anti-SARS-CoV-1 hIgG (negative control). One day later, mice were inoculated intranasally with Omicron BA.2 (10 4 PFU in 30 μl) and nasal turbinate (nt) and lungs were harvested on day 2 post-infection. (d) and (e) RT-qPCR analysis of Omicron BA.2 subgenomic (sg) RNA and plaque assay of infectious virus in the nt and/or lungs of TKI and DKI mice on day 2 post-infection. Data are presented as the mean ± SEM of 6–12 mice/group, pooled from two independent experiments. Circles represent individual mice and dotted lines indicate the limit of detection. Group means were compared by the Kruskal–Wallis and Dunn's multiple comparisons tests. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001.

Journal: eBioMedicine

Article Title: A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity

doi: 10.1016/j.ebiom.2025.105619

Figure Lengend Snippet: Functionality of hFcRn in hACE2-TMPRSS2-FCGRT TKI mice . (a) Pharmacokinetics of 1C3-YTE mAb, 1C3-WT mAb, and polyclonal human IgG (pAb) in TKI and DKI mice. Groups of treatment-naïve mice were injected intraperitoneally with 1 mg/kg mAbs or pAbs and bled at 3, 24, 72, 168, 336, and 504 h post-dose. Each mouse was bled at a maximum of two time points. Data are presented as the mean ± SEM of 3–8 mice/group/time point, pooled from two independent experiments. Group means at day 21 were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (b) Half-life of 1C3-YTE, 1C3-WT, and pAbs in TKI and DKI mice. Group means were compared by mixed-effect analysis and Šídák's correction. The open and filled bars represent DKI and TKI, respectively. (c) Experimental protocol for the data shown in (d and e). TKI and DKI mice were injected intraperitoneally (d) or intranasally (e) with 0.5 mg/kg of 1C3-YTE, 1C3-WT, or an anti-SARS-CoV-1 hIgG (negative control). One day later, mice were inoculated intranasally with Omicron BA.2 (10 4 PFU in 30 μl) and nasal turbinate (nt) and lungs were harvested on day 2 post-infection. (d) and (e) RT-qPCR analysis of Omicron BA.2 subgenomic (sg) RNA and plaque assay of infectious virus in the nt and/or lungs of TKI and DKI mice on day 2 post-infection. Data are presented as the mean ± SEM of 6–12 mice/group, pooled from two independent experiments. Circles represent individual mice and dotted lines indicate the limit of detection. Group means were compared by the Kruskal–Wallis and Dunn's multiple comparisons tests. ∗ P < 0.05, ∗∗ P < 0.01, ∗∗∗ P < 0.001.

Article Snippet: DKI mice (hACE2 and hTMPRSS2) and TKI mice (hACE2, hTMPRSS2, and hFCGRT; generated as described below) were bred at Synbal (San Diego, CA) and LJI, and housed in a specific pathogen-free facility under controlled temperature, humidity, and light (12 h on/off).

Techniques: Drug discovery, Injection, Negative Control, Infection, Quantitative RT-PCR, Plaque Assay, Virus