Journal: Alzheimer's & Dementia

Article Title: Repeated plasma p‐tau217 measurements to monitor clinical progression heterogeneity

doi: 10.1002/alz.70319

Figure Lengend Snippet: Between cluster comparison of plasma phosphorylated tau‐217 (p‐tau217) in Cohort 1 and Cohort 2. (A) Cohort 1 and (B) Cohort 2 show between‐cluster comparisons of plasma p‐tau217, with red dots indicating means. Cohort 1 utilized the University of Gothenburg in‐house p‐tau217 assay, whereas Cohort 2 utilized a commercially available kit by Janssen. Both used Quanterix Simoa HD‐X setups. All statistical tests were two‐sided and false‐discovery rate was used to adjust for multiple comparisons in each cohort. Due to differing assays and the range of pg/mL between assays, (D) shows the similarities of mean fold changes for cognitive decline clusters as compared to the stable cognition clusters in both cohorts. (C) Shows steeper plasma p‐tau217 increases over time in slow‐ and rapid‐decline clusters compared to the stable cognition cluster, with 95% confidence intervals. Unstandardized beta coefficients (b) illustrate individual slopes for each cluster. Created in BioRender. Kirsebom, B. (2025) https://BioRender.com/o54z804 .

Article Snippet: In Cohort 2, plasma p‐tau217 concentration was measured using Simoa HD‐X platform and the p‐tau217 kit (Janssen Sciences Ireland UC, a Johnson & Johnson company) according to the manufacturer's protocol.

Techniques: Comparison, Clinical Proteomics

Journal: Frontiers in Veterinary Science

Article Title: Design of a High-Throughput Real-Time PCR System for Detection of Bovine Respiratory and Enteric Pathogens

doi: 10.3389/fvets.2021.677993

Figure Lengend Snippet: Sensitivity and amplification efficiency of rtPCR assays on the Rotor-Gene Q and BioMark platforms.

Article Snippet: The repeatability of the rtPCR assays on the high-throughput rtPCR platform (BioMark HD) was evaluated by testing the positive controls in 13 separate chip runs.

Techniques: Amplification, Reverse Transcription Polymerase Chain Reaction

Journal: Frontiers in Veterinary Science

Article Title: Design of a High-Throughput Real-Time PCR System for Detection of Bovine Respiratory and Enteric Pathogens

doi: 10.3389/fvets.2021.677993

Figure Lengend Snippet: Heat map showing the specificity of the rtPCR assays on the high-throughput rtPCR system by testing known positive controls. To the left: rtPCR assays . At the top: the positive controls and a no-template control (NTC). Each square corresponds to a single rtPCR reaction. Cq values for each reaction are indicated by color; the corresponding color scale is presented in the legend on the right. A black square is considered a negative result. A black X is shown if the amplification curve deviates too much from an ideal amplification curve.

Article Snippet: The repeatability of the rtPCR assays on the high-throughput rtPCR platform (BioMark HD) was evaluated by testing the positive controls in 13 separate chip runs.

Techniques: Reverse Transcription Polymerase Chain Reaction, High Throughput Screening Assay, Control, Amplification

Journal: Frontiers in Veterinary Science

Article Title: Design of a High-Throughput Real-Time PCR System for Detection of Bovine Respiratory and Enteric Pathogens

doi: 10.3389/fvets.2021.677993

Figure Lengend Snippet: Feces and nasal swab samples analyzed on the high-throughput rtPCR system.

Article Snippet: The repeatability of the rtPCR assays on the high-throughput rtPCR platform (BioMark HD) was evaluated by testing the positive controls in 13 separate chip runs.

Techniques: Reverse Transcription Polymerase Chain Reaction

Journal: Frontiers in Veterinary Science

Article Title: Design of a High-Throughput Real-Time PCR System for Detection of Bovine Respiratory and Enteric Pathogens

doi: 10.3389/fvets.2021.677993

Figure Lengend Snippet: Test of repeatability of the rtPCR assays on the high-throughput rtPCR platform.

Article Snippet: The repeatability of the rtPCR assays on the high-throughput rtPCR platform (BioMark HD) was evaluated by testing the positive controls in 13 separate chip runs.

Techniques: Reverse Transcription Polymerase Chain Reaction, Control, Standard Deviation