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Image Search Results
Journal: European Journal of Nuclear Medicine and Molecular Imaging
Article Title: Combining [ 177 Lu]Lu-DOTA-TOC PRRT with PARP inhibitors to enhance treatment efficacy in small cell lung cancer
doi: 10.1007/s00259-024-06844-1
Figure Lengend Snippet: Determination of γH2AX foci formation and clonogenic survival in H446 cells. (A) Exemplary images of H446 cells after mono- or combination therapy directly after treatment or after a 23 h post-incubation time. (B) Number of γH2AX foci per cell after mono- or combination therapy directly after treatment or after a 23 h post-incubation time in medium. Displayed are mean ± SEM from 3 individual experiments. (C) Surviving fractions of H446 cells mono- or combination therapy. Displayed are mean values from 2 independent experiments
Article Snippet: 1:150 dilution),
Techniques: Incubation
Journal: European Journal of Nuclear Medicine and Molecular Imaging
Article Title: Combining [ 177 Lu]Lu-DOTA-TOC PRRT with PARP inhibitors to enhance treatment efficacy in small cell lung cancer
doi: 10.1007/s00259-024-06844-1
Figure Lengend Snippet: Immunohistochemistry of H69 tumors. Exemplary stainings of H69 tumors obtained from the single dose PRRT study ( n = 1 animal/group) for SSTR2, PARP1, γH2AX (DNA damage marker) and cleaved caspase 3 (apoptosis marker) are displayed. Scale bar = 100 µm. Brown color indicates positivity for the respective marker
Article Snippet: 1:150 dilution),
Techniques: Immunohistochemistry, Marker
Journal: bioRxiv
Article Title: Imaging-Guided Metabolic Radiosensitization of Pediatric Rhabdoid Tumors
doi: 10.1101/2024.08.09.607364
Figure Lengend Snippet: (A) Whole tissue imaging and ( B ) confocal micrographs of γ-H2AX immunofluorescence staining of all treatment groups on Day 9. (Insets) Stained A-204 tissue at high magnification. Scale bar = 50 µm for confocal images and scale bar = 1000 µm for whole tumor sections. (C) Quantification of γ-H2AX staining in whole tumor sections ( a ) and confocal micrographs ( b ) of all treatment groups. (D) H&E staining for heart, liver, kidney and muscle from various treatment groups. Scale bar=100 µm. Data represented as mean ± SD.
Article Snippet: Alexa Fluor 488 AffiniPure Donkey Anti-Rat lgG(H+L) (Lot 163136) and Rhodamine (TRITC) AffiniPure Donkey Anti-Rat lgG(H+L) (Lot 157518) were obtained from Jackson ImmunoResearch Inc.
Techniques: Imaging, Immunofluorescence, Staining