gö6983 Search Results


gö6983  (Santa Cruz Biotechnology)
91
Santa Cruz Biotechnology gö6983
Gö6983, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pmc04889354-343-48-51?v=Santa+Cruz+Biotechnology
Average 91 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
91/100 stars
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gö6983  (Axon Medchem LLC)
90
Axon Medchem LLC gö6983
Reagents and tools table
Gö6983, supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pmc11772670-76-0-2?v=Axon+Medchem+LLC
Average 90 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
90/100 stars
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gö6983  (Biomol GmbH)
90
Biomol GmbH gö6983
Reagents and tools table
Gö6983, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pmc02777682-82-0-9?v=Biomol+GmbH
Average 90 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
90/100 stars
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pan-pkc inhibitor gö6983  (STEMCELL Technologies Inc)
90
STEMCELL Technologies Inc pan-pkc inhibitor gö6983
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Pan Pkc Inhibitor Gö6983, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pmc11708431-34-23-29?v=STEMCELL+Technologies+Inc
Average 90 stars, based on 1 article reviews
pan-pkc inhibitor gö6983 - by Bioz Stars, 2026-07
90/100 stars
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protein kinase c (pkc) inhibitor, gö6983  (FUJIFILM)
90
FUJIFILM protein kinase c (pkc) inhibitor, gö6983
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Protein Kinase C (Pkc) Inhibitor, Gö6983, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/10__1113_slash_jp273883-158-57-60?v=FUJIFILM
Average 90 stars, based on 1 article reviews
protein kinase c (pkc) inhibitor, gö6983 - by Bioz Stars, 2026-07
90/100 stars
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gö6983  (Merck KGaA)
90
Merck KGaA gö6983
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Gö6983, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pm19853564-212-28-29?v=Merck+KGaA
Average 90 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
90/100 stars
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gö6983  (Cayman Chemical)
90
Cayman Chemical gö6983
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Gö6983, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pm30753865-46-0-4?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
90/100 stars
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gö 6983 g-7700  (LC Laboratories)
90
LC Laboratories gö 6983 g-7700
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Gö 6983 G 7700, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pmc11733117-323-0-2?v=LC+Laboratories
Average 90 stars, based on 1 article reviews
gö 6983 g-7700 - by Bioz Stars, 2026-07
90/100 stars
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gö6983  (Hello Bio Inc)
86
Hello Bio Inc gö6983
Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, <t>Gö6983</t> at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.
Gö6983, supplied by Hello Bio Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g%C3%B66983/pm42129557-684-0-3?v=Hello+Bio+Inc
Average 86 stars, based on 1 article reviews
gö6983 - by Bioz Stars, 2026-07
86/100 stars
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gö 6983  (MuseChem Chemicals)
N/A
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gö 6983  (Cayman Chemical)
N/A
Gö 6983 inhibits several isoforms of protein kinase C PKC IC 7 7 6 10 60 and 20 000 nM for PKCα PKCβ PKCγ PKCδ PKCζ and PKCμ respectively It provides cardioprotective effects in myocardial
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Reagents and tools table

Journal: EMBO Reports

Article Title: Transposable element activity captures human pluripotent cell states

doi: 10.1038/s44319-024-00343-y

Figure Lengend Snippet: Reagents and tools table

Article Snippet: Gö6983 , Axon Medchem , 2466.

Techniques: Recombinant, Modification, Purification, Sequencing, Knock-Out, Software, Electroporation

Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, Gö6983 at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.

Journal: Journal of Molecular and Cellular Cardiology Plus

Article Title: Transcriptomics reveal stretched human pluripotent stem cell-derived cardiomyocytes as an advantageous hypertrophy model

doi: 10.1016/j.jmccpl.2022.100020

Figure Lengend Snippet: Effects of p38 mitogen-activated protein kinase (p38 MAPK), mitogen-activated protein kinase kinase 1/2 (MEK1/2) and protein kinase C (PKC) inhibitors on stretch-induced hypertrophic gene expression in human pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The following inhibitors were utilized: SB203580 at 10 μM to inhibit p38 MAPK, U0126 at 10 μM to inhibit MEK1/2, Gö6983 at 1 μM to inhibit all PKC isoforms and Gö6976 at 1 μM to inhibit classical PKC isoforms. Natriuretic peptide B ( NPPB ; A), skeletal muscle alpha actin 1 ( ACTA1 ; B), galanin ( GAL ; C) and long intergenic non-protein coding RNA 648 ( LINC00648 ; D) RNA expression was measured with qRT–PCR after a 24-h cyclic mechanical stretch. The results are presented as fold change relative to the unstretched control. The data are shown as mean ± standard error of the mean, and values from individual experiments are presented as dots ( n = 5, except for SB203580 and Gö6976 n = 4; where n represents biological replicates of cells from individual differentiations). * p < 0.05, ** p < 0.01 vs. unstretched DMSO, † p < 0.05 vs. stretched DMSO, Mann–Whitney U test.

Article Snippet: The mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor U0126 and the p38 MAPK inhibitor SB203580 were purchased from Tocris Bioscience (Bristol, UK), the pan-PKC inhibitor Gö6983 was purchased from STEMCELL Technologies (Vancouver, Canada) and the classical PKC inhibitor Gö6976 was purchased from Merck (Darmstadt, Germany).

Techniques: Gene Expression, Derivative Assay, RNA Expression, Quantitative RT-PCR, Control, MANN-WHITNEY