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Image Search Results
Journal: The Journal of Biological Chemistry
Article Title: Conformationally Trapping the Actin-binding Cleft of Myosin with a Bifunctional Spin Label
doi: 10.1074/jbc.M112.428565
Figure Lengend Snippet: Bifunctional spin labeling. A, Dicty myosin II catalytic domain crosslinked by a BSL, shown in red (space-filling), between engineered cysteine residues 416 and 583 in the U50 (green) and L50 (blue) domains of the actin-binding cleft. BSL was modeled on crystal structure 1FMV using Discovery Studio 2.5.5 and visualized using PyMOL. B, conventional (V1) EPR spectrum of the labeled protein in solution.
Article Snippet: Molecular Modeling Spin labels were modeled on crystal structure 1FMV using Discovery Studio 2.5.5 (Accelrys Software Inc., San Diego) and visualized using the
Techniques: Labeling, Binding Assay