gp130 Search Results


recombinant mouse sgp130 fc chimera  (R&D Systems)
93
R&D Systems recombinant mouse sgp130 fc chimera
(A-C) CCL2 and TNFα levels in cell-free supernatants 24 hr after stimulation with rIL-6, rIL-6 plus sIL-6R, rIL-6 plus sIL-6R plus <t>sgp130,</t> <t>sgp130,</t> or PBS; data from 3 independent sets of experiments showing an increase in CCL2 secretion from gingival cells stimulated with rIL-6 plus sIL-6R; rIL-6 plus sIL-6R plus <t>sgp130;</t> or sgp130 compared to PBS control cultures. (D) Neutralization of sgp130 by anti-gp130 antibody causes an increase in CCL2 secretion. (E) A gingival cell line stained with sgp130 indicated that about one-fifth of the cells express gp130. (F) Cell supernatants used for CCL2 assays had no detectable TNFα production.
Recombinant Mouse Sgp130 Fc Chimera, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hcch  (Sino Biological)
89
Sino Biological hcch

Hcch, supplied by Sino Biological, used in various techniques. Bioz Stars score: 89/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gp130  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc gp130

Gp130, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
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gp130  (Santa Cruz Biotechnology)
94
Santa Cruz Biotechnology gp130
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Gp130, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gp130/product/Santa Cruz Biotechnology
Average 94 stars, based on 1 article reviews
gp130 - by Bioz Stars, 2026-03
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21175 1 ap  (Proteintech)
94
Proteintech 21175 1 ap
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
21175 1 Ap, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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rabbit polyclonal anti gp130  (Santa Cruz Biotechnology)
95
Santa Cruz Biotechnology rabbit polyclonal anti gp130
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Rabbit Polyclonal Anti Gp130, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cd130 il6st 100 ng  (OriGene)
89
OriGene cd130 il6st 100 ng
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Cd130 Il6st 100 Ng, supplied by OriGene, used in various techniques. Bioz Stars score: 89/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gp 130  (Bio-Techne corporation)
93
Bio-Techne corporation gp 130
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Gp 130, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gp 130/product/Bio-Techne corporation
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gp130 sirnas  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology gp130 sirnas
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Gp130 Sirnas, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti phospho gp130  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology anti phospho gp130
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Anti Phospho Gp130, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1 5 bis boc1 5 10 spermidine boc spd  (Chem Impex International)
95
Chem Impex International 1 5 bis boc1 5 10 spermidine boc spd
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
1 5 Bis Boc1 5 10 Spermidine Boc Spd, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti il6st  (Proteintech)
93
Proteintech anti il6st
Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with <t>GP130</t> (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.
Anti Il6st, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A-C) CCL2 and TNFα levels in cell-free supernatants 24 hr after stimulation with rIL-6, rIL-6 plus sIL-6R, rIL-6 plus sIL-6R plus sgp130, sgp130, or PBS; data from 3 independent sets of experiments showing an increase in CCL2 secretion from gingival cells stimulated with rIL-6 plus sIL-6R; rIL-6 plus sIL-6R plus sgp130; or sgp130 compared to PBS control cultures. (D) Neutralization of sgp130 by anti-gp130 antibody causes an increase in CCL2 secretion. (E) A gingival cell line stained with sgp130 indicated that about one-fifth of the cells express gp130. (F) Cell supernatants used for CCL2 assays had no detectable TNFα production.

Journal:

Article Title: Porphyromonas gingivalis lipopolysaccharide induces tumor necrosis factor-α and interleukin-6 (IL-6) secretion and CCL25 gene expression in mouse primary gingival cell lines: IL-6-driven activation of CCL2

doi:

Figure Lengend Snippet: (A-C) CCL2 and TNFα levels in cell-free supernatants 24 hr after stimulation with rIL-6, rIL-6 plus sIL-6R, rIL-6 plus sIL-6R plus sgp130, sgp130, or PBS; data from 3 independent sets of experiments showing an increase in CCL2 secretion from gingival cells stimulated with rIL-6 plus sIL-6R; rIL-6 plus sIL-6R plus sgp130; or sgp130 compared to PBS control cultures. (D) Neutralization of sgp130 by anti-gp130 antibody causes an increase in CCL2 secretion. (E) A gingival cell line stained with sgp130 indicated that about one-fifth of the cells express gp130. (F) Cell supernatants used for CCL2 assays had no detectable TNFα production.

Article Snippet: Reagents used in this study included ultrapure P. gingivalis LPS (Invitrogen; San Diego; CA) and E. coli LPS (Sigma); recombinant IL-6 (rIL-6) (<0.01 ng endotoxin per μg cytokine (eBioscience; San Diego, CA); sIL-6R (<0.0 EU endotoxin per 1 μg cytokine receptor) (R&D Systems; Minneapolis, MN); two preparations of sgp130: recombinant human sgp130 (<1.0 EU endotoxin per 1 μg receptor) (R&D Systems), and recombinant mouse sgp130/Fc chimera (<1.0 ng endotoxin per 1 μg receptor) (R&D systems).

Techniques: Control, Neutralization, Staining

Stimulatory effects on CCL2 secretion from gingival cell lines

Journal:

Article Title: Porphyromonas gingivalis lipopolysaccharide induces tumor necrosis factor-α and interleukin-6 (IL-6) secretion and CCL25 gene expression in mouse primary gingival cell lines: IL-6-driven activation of CCL2

doi:

Figure Lengend Snippet: Stimulatory effects on CCL2 secretion from gingival cell lines

Article Snippet: Reagents used in this study included ultrapure P. gingivalis LPS (Invitrogen; San Diego; CA) and E. coli LPS (Sigma); recombinant IL-6 (rIL-6) (<0.01 ng endotoxin per μg cytokine (eBioscience; San Diego, CA); sIL-6R (<0.0 EU endotoxin per 1 μg cytokine receptor) (R&D Systems; Minneapolis, MN); two preparations of sgp130: recombinant human sgp130 (<1.0 EU endotoxin per 1 μg receptor) (R&D Systems), and recombinant mouse sgp130/Fc chimera (<1.0 ng endotoxin per 1 μg receptor) (R&D systems).

Techniques:

Journal: Cell Reports Methods

Article Title: Sequence enrichment profiles enable target-agnostic antibody generation for a broad range of antigens

doi: 10.1016/j.crmeth.2023.100475

Figure Lengend Snippet:

Article Snippet: CD130 , Sino Biological , Cat# 10974-HCCH.

Techniques: Produced, Recombinant, Sequencing, Software

Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with GP130 (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.

Journal: The International journal of developmental biology

Article Title: Activated Notch1 is a stronger astrocytic stimulus than leukemia inhibitory factor for rat neural stem cells.

doi: 10.1387/ijdb.092869nr

Figure Lengend Snippet: Fig. 1. Cortical NSC respond to LIF and CNTF stimulation. Proliferating neural progenitors/NSC expressed Nestin (A,B) together with GP130 (A) or LIFRβ (B). In control cultures, no signal for phospho (p)STAT3 was detected (C). After addition of LIF, NSC show nuclear pSTAT3. Accordingly, in immunoblot assays, control (CTL) cells have non-phosphorylated STAT3, and 10 ng/ml CNTF or the indicated LIF concentrations induced phosphorylation of STAT3 (D). The transcriptional activation of Socs3 is only found in cells stimulated with LIF or CNTF (E). Images are representative of 3 independent experiments performed in duplicate. Scale bars represent 20 μm for A and 50 μm for B. -RT, RNA without reverse transcriptase.

Article Snippet: Other cell markers were immunodetected with the following antibodies: Nestin (Developmental Studies Hybridoma Bank), β-Tubulin-III (mouse or rabbit TUJ1, Covance), GFAP (rabbit, DAKO; rat, Zymed), pSTAT3 (Cell Signaling), Sox2 (Chemicon), GP130 (Santa Cruz Biotechnology) and LIFRβ (Santa Cruz Biotechnology).

Techniques: Control, Western Blot, Phospho-proteomics, Activation Assay, Reverse Transcription