glycopolymers Search Results


90
Verlag GmbH glycopolymers 1-30
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BioMimetic Therapeutics heparan sulfate-functionalized glycopolymers
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Glycomimetics inc multivalent pendant saccharide glycopolymer
Multivalent Pendant Saccharide Glycopolymer, supplied by Glycomimetics inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Feto Maternal and GenetYX Center glycopolymers
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Glycopolymers, supplied by Feto Maternal and GenetYX Center, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glycopolymers/glycopolymers/pmc05642150-169-12-35
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BioMimetic Therapeutics glycopolymer-based biomimetic nanomedicine
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Glycopolymer Based Biomimetic Nanomedicine, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glycopolymers/glycopolymer+based+biomimetic+nanomedicine/pm34928129-434-34-33
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BioMimetic Therapeutics glycopolymers
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Glycopolymers, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioMimetic Therapeutics glycopolymer-polypeptide triblock copolymer
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Glycopolymer Polypeptide Triblock Copolymer, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Polyneuron Pharmaceuticals selective antibody-scavenging glycopolymer
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Selective Antibody Scavenging Glycopolymer, supplied by Polyneuron Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Lectinity Holding Inc streptavidin-peroxidase coupled polyacrylamide glycopolymer
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Streptavidin Peroxidase Coupled Polyacrylamide Glycopolymer, supplied by Lectinity Holding Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Verlag GmbH pcl-containing miktoarm glycopolymer
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Pcl Containing Miktoarm Glycopolymer, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
NanoVector sirna labeled-oxaborole glycopolymer 2 conjugate
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Sirna Labeled Oxaborole Glycopolymer 2 Conjugate, supplied by NanoVector, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Lectinity Holding Inc manβ1- 4glcnacβ
Representative chemical structures of the mannose <t>glycopolymers.</t> R = Br in the initiator structure.
Manβ1 4glcnacβ, supplied by Lectinity Holding Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Representative chemical structures of the mannose glycopolymers. R = Br in the initiator structure.

Journal: Chemical Science

Article Title: Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN † †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01515a Click here for additional data file.

doi: 10.1039/c7sc01515a

Figure Lengend Snippet: Representative chemical structures of the mannose glycopolymers. R = Br in the initiator structure.

Article Snippet: Importantly, IL-10 levels rise and IL-12 levels fall in response to the glycopolymers and this cytokine release pattern is reminiscent of tissue environments associated with active wound healing, anti-inflammation, and also healthy pregnancy at the feto-maternal interface.

Techniques:

Concentration-dependent glycopolymer binding to DCs. Dendritic cells were labeled with the indicated concentration of FITC-labeled glycopolymers/glycoprotein (Panel A – Linear P1 ; Panel B – 5-arm star P2 ; Panel C – 8-arm star P3 ; and Panel D – gp120) and analyzed by flow cytometry. The data are representative of one of 3 donors.

Journal: Chemical Science

Article Title: Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN † †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01515a Click here for additional data file.

doi: 10.1039/c7sc01515a

Figure Lengend Snippet: Concentration-dependent glycopolymer binding to DCs. Dendritic cells were labeled with the indicated concentration of FITC-labeled glycopolymers/glycoprotein (Panel A – Linear P1 ; Panel B – 5-arm star P2 ; Panel C – 8-arm star P3 ; and Panel D – gp120) and analyzed by flow cytometry. The data are representative of one of 3 donors.

Article Snippet: Importantly, IL-10 levels rise and IL-12 levels fall in response to the glycopolymers and this cytokine release pattern is reminiscent of tissue environments associated with active wound healing, anti-inflammation, and also healthy pregnancy at the feto-maternal interface.

Techniques: Concentration Assay, Binding Assay, Labeling, Flow Cytometry

Effects of glycopolymers on cytokine secretion by activated DCs. Cells were incubated with GPs before activation with LPS and IFN-γ and multiplex cytokine assay. IL-10 secretion was significantly increased in DC cultures from 4 donors incubated with 8-arm star P3 and 5-arm star P2 GPs at 10 μg ml –1 compared with controls, but not with linear GP P1 (Panel A). IL-12p70 secretion was significantly decreased compared to controls in cells exposed to increasing concentrations of linear GP P1 (Panel B), 5-arm star GP P2 (Panel C) and 8-arm star GP P3 (Panel D) (all P values calculated from paired t -tests).

Journal: Chemical Science

Article Title: Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN † †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01515a Click here for additional data file.

doi: 10.1039/c7sc01515a

Figure Lengend Snippet: Effects of glycopolymers on cytokine secretion by activated DCs. Cells were incubated with GPs before activation with LPS and IFN-γ and multiplex cytokine assay. IL-10 secretion was significantly increased in DC cultures from 4 donors incubated with 8-arm star P3 and 5-arm star P2 GPs at 10 μg ml –1 compared with controls, but not with linear GP P1 (Panel A). IL-12p70 secretion was significantly decreased compared to controls in cells exposed to increasing concentrations of linear GP P1 (Panel B), 5-arm star GP P2 (Panel C) and 8-arm star GP P3 (Panel D) (all P values calculated from paired t -tests).

Article Snippet: Importantly, IL-10 levels rise and IL-12 levels fall in response to the glycopolymers and this cytokine release pattern is reminiscent of tissue environments associated with active wound healing, anti-inflammation, and also healthy pregnancy at the feto-maternal interface.

Techniques: Incubation, Activation Assay, Multiplex Assay, Cytokine Assay