gip Search Results


gip 1 39  (Tocris)
96
Tocris gip 1 39
Gip 1 39, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gip human 22 51 igg  (R&D Systems)
99
R&D Systems gip human 22 51 igg
Gip Human 22 51 Igg, supplied by R&D Systems, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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d ala2 gip  (Tocris)
91
Tocris d ala2 gip
D Ala2 Gip, supplied by Tocris, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gip  (Novus Biologicals)
90
Novus Biologicals gip
Gip, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene exp gip hs00175030 m1  (Thermo Fisher)
91
Thermo Fisher gene exp gip hs00175030 m1
Gene Exp Gip Hs00175030 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti cxcl10  (Proteintech)
94
Proteintech anti cxcl10
Anti Cxcl10, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cxcl10 ip10  (Proteintech)
93
Proteintech cxcl10 ip10
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Cxcl10 Ip10, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cxcl10 elisa  (OriGene)
93
OriGene cxcl10 elisa
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Cxcl10 Elisa, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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rabbit anti gip antibody  (Biosynth Carbosynth)
91
Biosynth Carbosynth rabbit anti gip antibody
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Rabbit Anti Gip Antibody, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hsc1 hs4 gip  (Addgene inc)
93
Addgene inc hsc1 hs4 gip
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Hsc1 Hs4 Gip, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human cxcl10 ip 10 elisa kit  (Proteintech)
94
Proteintech human cxcl10 ip 10 elisa kit
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Human Cxcl10 Ip 10 Elisa Kit, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gnai2 11136 1 ap proteintech rabbit  (Proteintech)
93
Proteintech gnai2 11136 1 ap proteintech rabbit
BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and <t>CXCL10</t> in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).
Gnai2 11136 1 Ap Proteintech Rabbit, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and CXCL10 in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).

Journal: Advanced Science

Article Title: BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti‐PD‐1/PD‐L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity

doi: 10.1002/advs.202207155

Figure Lengend Snippet: BCAT2 varies expression patterns of CD8 + T‐cell‐related chemokines and inhibits cytotoxic capacity of CTLs. A,B) Heatmaps of ProcartaPlex multiple immunoassays display secretion variation of common cytokines and chemokines in BCAT2 OE, BCAT2 KD and negative control groups ( n = 3 per group). C,D) Histograms show normalized mRNA expression levels and protein secretion concentrations of CCL3, CCL4, CCL5, CXCL9, and CXCL10 in BCAT2 OE (left), BCAT2 KD (right) and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01; *** p < 0.001. E) Chemotaxis assay indicates different chemotaxis ability of CTLs in BCAT2 OE, BCAT2 KD, and negative control groups ( n = 3 per group). * p < 0.05; ** p < 0.01. F) T‐cell‐mediated cancer cell killing assay indicates different killing abilities of T cells cocultured with BCAT2 OE, BCAT2 KD, and negative control cell lines ( n = 3 per group). G) Flow cytometry analysis indicates different activities of CD8 + T cells in different coculture groups ( n = 3 per group).

Article Snippet: Concentrations of CCL3, CCL4, CCL5, CXCL9 (MIG), and CXCL10 (IP10) in human bladder cancer cell culture supernatants were determined by human ELISA kits following manufacturer's protocol (Proteintech, USA).

Techniques: Expressing, Negative Control, Chemotaxis Assay, Flow Cytometry