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Image Search Results
Journal: Frontiers in Immunology
Article Title: Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells
doi: 10.3389/fimmu.2021.669906
Figure Lengend Snippet: NFKB1 transcription factor network and disease associations. (A) Lisa analysis identifying transcription factors associated with the expression LPS dependent of genes differentially expressed in NFKB1 -/- cells (p < 0.01). Top most significant factors indicated by orange symbols. (B) Identification of disease associated gene signatures in the GeneRif database with significant similarity to the transcriptional signature of LPS-stimulated NFKB1 -/- cells (q value < 0.05). Heatmap on right shows selected genes associated with the severe combined and common variable immunodeficiency disease signatures, Z-score normalized.
Article Snippet: For
Techniques: Expressing