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Image Search Results
Journal: Frontiers in Molecular Neuroscience
Article Title: A DNA Methylation Signature of Addiction in T Cells and Its Reversal With DHEA Intervention
doi: 10.3389/fnmol.2018.00322
Figure Lengend Snippet: DNA methylation differences associated with addiction. (A) Box plot of average methylation of sites that are differentially methylated between addicted and healthy controls. Bottom panel: the average methylation of genes that become less methylated (hypomethylation) and more methylated (hypermethylation) in addicts ∗∗∗ p < 2.2E-16; Mann–Whitney test. (B) Heat map showing clustering by one minus Pearson correlations of healthy controls and addicts using the 5,532 differentially methylated genes (4,458 probes were hypomethylated and 1,074 hypermethylated in addicts).
Article Snippet: Hierarchical clustering was performed using one
Techniques: DNA Methylation Assay, Methylation, MANN-WHITNEY