fluprostenol Search Results



90
MedChemExpress travoprost
Top ranked hit-list for binding site A_ref.
Travoprost, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluprostenol/Travoprost/pmc06543810-254-0-1
Average 90 stars, based on 1 article reviews
travoprost - by Bioz Stars, 2026-09
90/100 stars
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90
Biomol GmbH fluprostenol
Top ranked hit-list for binding site A_ref.
Fluprostenol, supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluprostenol/fluprostenol/pm15087429-52-0-6
Average 90 stars, based on 1 article reviews
fluprostenol - by Bioz Stars, 2026-09
90/100 stars
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90
ICI Pharmaceuticals fluprostenol equimate
Top ranked hit-list for binding site A_ref.
Fluprostenol Equimate, supplied by ICI Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluprostenol/fluprostenol+equimate/pm00573325-42-22-24
Average 90 stars, based on 1 article reviews
fluprostenol equimate - by Bioz Stars, 2026-09
90/100 stars
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N/A
Fluprostenol is a metabolically stable analog of PGF with potent FP receptor agonist activity Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture
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N/A
Fluprostenol-d|4|contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of fluprostenol by GC- or LC-mass spectrometry. Fluprostenol is a metabolically
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N/A
The optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. (+)-Fluprostenol methyl amide is a methyl amide analog of (+)-fluprostenol. There are no published reports on
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N/A
15-keto Fluprostenol isopropyl ester is a metabolite of Travoprost with weak FP receptor binding affinity. Travoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Oxidation of the
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N/A
Travoprost is the Alcon trade name for fluprostenol isopropyl ester an F series prostaglandin analog which has been approved for use as an ocular hypotensive drug Fluprostenol isopropyl ester is a prodrug which is converted
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N/A
(+)-Fluprostenol methyl ester is an F-series prostaglandin analog used as a luteolytic. This compound is a methyl ester analog of fluprostenol .
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Image Search Results


Top ranked hit-list for binding site A_ref.

Journal: Frontiers in Pharmacology

Article Title: Computational Identification of Novel Kir6 Channel Inhibitors

doi: 10.3389/fphar.2019.00549

Figure Lengend Snippet: Top ranked hit-list for binding site A_ref.

Article Snippet: Travoprost (MedChemExpress, Monmouth Junction, NJ, United States) was dissolved in DMSO at 10 mM.

Techniques: Binding Assay

Indication, description, and relevant side effect of the top ranked hit-list compounds at binding site A_ref.

Journal: Frontiers in Pharmacology

Article Title: Computational Identification of Novel Kir6 Channel Inhibitors

doi: 10.3389/fphar.2019.00549

Figure Lengend Snippet: Indication, description, and relevant side effect of the top ranked hit-list compounds at binding site A_ref.

Article Snippet: Travoprost (MedChemExpress, Monmouth Junction, NJ, United States) was dissolved in DMSO at 10 mM.

Techniques: Binding Assay, Infection, Inhibition

Inhibition of Kir6.2/SUR2A carried I KATP by Travoprost, Betaxolol, and Ritodrine. (A) Current traces of Kir6.2/SUR2A channels in the inside-out orientation exposed to Travoprost, Betaxolol, or Ritodrine at the indicated drug concentrations (0, 3 and 30 μM). Dotted horizontal line at 0 pA. (B) Normalized block of inward (black bars, at –80 mV) and outward (open bars, at +50 mV) currents with 30 μM of the indicated drug. * P < 0.001 (paired T -test, inward vs. outward; n = 8, n = 11, and n = 9 for Travoprost, Betaxolol, and Ritodrine, respectively. (C) IC 50 curves of outward components of Kir6.2/SUR2A in response to different concentrations of Travoprost (open squares; n = 8), Betaxolol [black triangles; n = 11 or n = 7 (100 μM)] and Ritodrine [black circles; n = 9 (control and 1 μM), n = 8 (0.3 μM), or n = 7 (3, 10, 30 μM)]. Data were fitted with Hill equation to estimate the IC 50 values. Data in panels b and c are shown as mean ± SEM. The data in panel B are extracted from the ramp recordings similar to traces as shown in panel A.

Journal: Frontiers in Pharmacology

Article Title: Computational Identification of Novel Kir6 Channel Inhibitors

doi: 10.3389/fphar.2019.00549

Figure Lengend Snippet: Inhibition of Kir6.2/SUR2A carried I KATP by Travoprost, Betaxolol, and Ritodrine. (A) Current traces of Kir6.2/SUR2A channels in the inside-out orientation exposed to Travoprost, Betaxolol, or Ritodrine at the indicated drug concentrations (0, 3 and 30 μM). Dotted horizontal line at 0 pA. (B) Normalized block of inward (black bars, at –80 mV) and outward (open bars, at +50 mV) currents with 30 μM of the indicated drug. * P < 0.001 (paired T -test, inward vs. outward; n = 8, n = 11, and n = 9 for Travoprost, Betaxolol, and Ritodrine, respectively. (C) IC 50 curves of outward components of Kir6.2/SUR2A in response to different concentrations of Travoprost (open squares; n = 8), Betaxolol [black triangles; n = 11 or n = 7 (100 μM)] and Ritodrine [black circles; n = 9 (control and 1 μM), n = 8 (0.3 μM), or n = 7 (3, 10, 30 μM)]. Data were fitted with Hill equation to estimate the IC 50 values. Data in panels b and c are shown as mean ± SEM. The data in panel B are extracted from the ramp recordings similar to traces as shown in panel A.

Article Snippet: Travoprost (MedChemExpress, Monmouth Junction, NJ, United States) was dissolved in DMSO at 10 mM.

Techniques: Inhibition, Blocking Assay, Control

Inhibition of C166S (Kir6.2) and S1020P (SUR2A) by Rosiglitazone, Travoprost, Betaxolol, and Ritodrine. IC 50 curves of outward components of Kir6.2/SUR2A (WT, C166S Kir6.2, and S1020P SUR2A) in response to different concentrations of Rosiglitazone, Travoprost, Betaxolol, and Ritodrine. N -values are: WT, C166S, and S1020P, respectively: Rosiglitazone n = 8, 8, 6; Travoprost n = 8, 7, 11; Betaxolol n = 11, 7, 7; and Ritodrine n = 9, 8, 7. Data were fitted with Hill equation to estimate the IC 50 values. Data are shown as mean ± SEM.

Journal: Frontiers in Pharmacology

Article Title: Computational Identification of Novel Kir6 Channel Inhibitors

doi: 10.3389/fphar.2019.00549

Figure Lengend Snippet: Inhibition of C166S (Kir6.2) and S1020P (SUR2A) by Rosiglitazone, Travoprost, Betaxolol, and Ritodrine. IC 50 curves of outward components of Kir6.2/SUR2A (WT, C166S Kir6.2, and S1020P SUR2A) in response to different concentrations of Rosiglitazone, Travoprost, Betaxolol, and Ritodrine. N -values are: WT, C166S, and S1020P, respectively: Rosiglitazone n = 8, 8, 6; Travoprost n = 8, 7, 11; Betaxolol n = 11, 7, 7; and Ritodrine n = 9, 8, 7. Data were fitted with Hill equation to estimate the IC 50 values. Data are shown as mean ± SEM.

Article Snippet: Travoprost (MedChemExpress, Monmouth Junction, NJ, United States) was dissolved in DMSO at 10 mM.

Techniques: Inhibition