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In vivo dynamics of infection during drug treatment. Drug treatment was initiated 24 h p.i. [intraperitoneal injection of <t>fluconazole</t> (FLC): 10 mg/kg (A) , caspofungin (CAS): 1 mg/kg (B) ] and repeated at 48 h p.i. for FLC and 48 h p.i., and 96 h p.i. for CAS. (Mann-Whitney unpaired test, p -value: * < 0.05, ** < 0.01, **** < 0.0001).
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In vivo dynamics of infection during drug treatment. Drug treatment was initiated 24 h p.i. [intraperitoneal injection of <t>fluconazole</t> (FLC): 10 mg/kg (A) , caspofungin (CAS): 1 mg/kg (B) ] and repeated at 48 h p.i. for FLC and 48 h p.i., and 96 h p.i. for CAS. (Mann-Whitney unpaired test, p -value: * < 0.05, ** < 0.01, **** < 0.0001).
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In vivo dynamics of infection during drug treatment. Drug treatment was initiated 24 h p.i. [intraperitoneal injection of <t>fluconazole</t> (FLC): 10 mg/kg (A) , caspofungin (CAS): 1 mg/kg (B) ] and repeated at 48 h p.i. for FLC and 48 h p.i., and 96 h p.i. for CAS. (Mann-Whitney unpaired test, p -value: * < 0.05, ** < 0.01, **** < 0.0001).
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Image Search Results


In vivo dynamics of infection during drug treatment. Drug treatment was initiated 24 h p.i. [intraperitoneal injection of fluconazole (FLC): 10 mg/kg (A) , caspofungin (CAS): 1 mg/kg (B) ] and repeated at 48 h p.i. for FLC and 48 h p.i., and 96 h p.i. for CAS. (Mann-Whitney unpaired test, p -value: * < 0.05, ** < 0.01, **** < 0.0001).

Journal: Frontiers in Microbiology

Article Title: Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging

doi: 10.3389/fmicb.2017.01478

Figure Lengend Snippet: In vivo dynamics of infection during drug treatment. Drug treatment was initiated 24 h p.i. [intraperitoneal injection of fluconazole (FLC): 10 mg/kg (A) , caspofungin (CAS): 1 mg/kg (B) ] and repeated at 48 h p.i. for FLC and 48 h p.i., and 96 h p.i. for CAS. (Mann-Whitney unpaired test, p -value: * < 0.05, ** < 0.01, **** < 0.0001).

Article Snippet: For drug treatments, mice were injected intraperitoneally daily starting 24 h post-infection (p.i.) with 100 μl of fluconazole (FLC: 10 mg/kg; Toronto Research Chemicals) or 100 μl of caspofungin (CAS: 1 mg/kg; Cancidas® Merck, Switzerland).

Techniques: In Vivo, Infection, Injection, MANN-WHITNEY