fasentin Search Results


92
MedChemExpress fasentin
Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: <t>MSNBA,</t> <t>CytB,</t> GluAm, G2iA, and <t>fasentin.</t> Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.
Fasentin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Tocris fasentin
Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: <t>MSNBA,</t> <t>CytB,</t> GluAm, G2iA, and <t>fasentin.</t> Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.
Fasentin, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Tocris fasentin fsn 27
Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: <t>MSNBA,</t> <t>CytB,</t> GluAm, G2iA, and <t>fasentin.</t> Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.
Fasentin Fsn 27, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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92
Santa Cruz Biotechnology fasentin fsn 27
Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: <t>MSNBA,</t> <t>CytB,</t> GluAm, G2iA, and <t>fasentin.</t> Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.
Fasentin Fsn 27, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Merck KGaA fasentin
Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: <t>MSNBA,</t> <t>CytB,</t> GluAm, G2iA, and <t>fasentin.</t> Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.
Fasentin, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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N/A
Inhibitor of glucose uptake via GLUT1 and GLUT4 transporters, promoting intracellular glucose deprivation. The compound is a chemical sensitizer to the FAS cell death receptor and is able to break down the resistance of caspase
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N/A
Fasentin is a GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Fasentin sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) via regulating the extrinsic apoptotic pathway downstream of TNF
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N/A
Fasentin is a potent glucose uptake inhibitor. It inhibits GLUT-1/GLUT-4 transporters.
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Image Search Results


Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: MSNBA, CytB, GluAm, G2iA, and fasentin. Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.

Journal: ACS chemical biology

Article Title: Discrimination of GLUTs by Fructose Isomers Enables Simultaneous Screening of GLUT5 and GLUT2 Activity in Live Cells

doi: 10.1021/acschembio.2c00682

Figure Lengend Snippet: Changes for P1–P3 uptake in MCF7 cells in the presence of inhibitors: MSNBA, CytB, GluAm, G2iA, and fasentin. Cell fluorescence was recorded using confocal microscopy. Fluorescence images (Figure S11) for every condition (DAPI, 60× objective, same laser intensity and exposure time) were quantified using ImageJ. Graphical data represents an average fluorescence of 7–20 cells from two repeats. Relative fluorescence for every probe in every condition was derived by normalizing the derived CTCF/area value for probe + inhibitor combination by the CTCF/area of the corresponding control (P1, P2, or P3). Error bars represent relative standard deviation between two independent experiments. A two-tailed t-test was used to detect statistically significant differences: *p ~ 0.01–0.001, **p ~ 0.001–0.0001.

Article Snippet: Cytochalasin B (CytB), MSNBA, glucosamine (GluAm), and fasentin were purchased from Sigma-Aldrich, MolPort, Chem-Impex International, and MedChemExpress, respectively.

Techniques: Fluorescence, Confocal Microscopy, Derivative Assay, Control, Standard Deviation, Two Tailed Test