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Selleck Chemicals
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Accustandard Inc
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Sakura Finetek
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Moduline Systems
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Siemens AG
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Wolters Kluwer Health
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HiMedia Laboratories
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Cayman Chemical
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Siemens Healthineers
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Clinical and Laboratory Standards Institute
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Charles River Laboratories
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Image Search Results
Journal: Nucleic Acids Research
Article Title: Mammalian CST averts replication failure by preventing G-quadruplex accumulation
doi: 10.1093/nar/gkz264
Figure Lengend Snippet: CST is recruited to telomeres after G4 stabilization. ( A ) Co-localization of FLAG-STN1 and telomeres in HeLa cells after treatment with G4 stabilizers TmPyP4 or PDS. Red, FLAG-STN1 immunostaining; green, telomere FISH; blue, DAPI. ( B ) Quantification showing increased numbers of FLAG-STN1 foci following treatment with TmPyP4 or PDS. ( C ) Quantification of FLAG-STN1 foci at telomeres after treatment with G4 ligands. (D, E) ChIP analysis to examine changes in localization of the indicated proteins to telomeres or Alu repeats after PDS treatment with or without 10 μM ATM inhibitor (KU55933) and 2μM ATR inhibitor (ETP-46464). ( D ) Slot-blot analysis of DNA precipitated with antibody to TPP1, FLAG (STN1), pol α, pol δ or pol ϵ. Blot was hybridized with a telomere (Telo) or Alu probe. ( E ) Quantification of ChIP. Telo/Alu ChIP signals and Tubulin ChIP-PCR value were normalized against input DNA. Values are mean ± SEM, n = 3 experiments, * P < 0.05. Related to .
Article Snippet: For ATM and ATR inhibition: 10 μM
Techniques: Immunostaining, Dot Blot
Journal: Research and Practice in Thrombosis and Haemostasis
Article Title: Thrombin generation measured on ST Genesia, a new platform in the coagulation routine lab: Assessment of analytical and between‐subject variation
doi: 10.1002/rth2.12654
Figure Lengend Snippet: Comparison between TG performed on CAT (PPPLow reagent) and on ST Genesia using the Bleedscreen reagent. The correlations between the mean of eight values (four duplicates) of each sample measured on each instrument are shown. TG, thrombin generation
Article Snippet: This methodology has been widely used as a research tool on various platforms: calibrated automated
Techniques: Comparison