Journal: Plants

Article Title: Profiling of Flavonoid and Antioxidant Activity of Fruit Tissues from 27 Chinese Local Citrus Cultivars

doi: 10.3390/plants9020196

Figure Lengend Snippet: Characteristic UPLC-PDA chromatogram of YXWL ( C. reticulata ) peel, pulp, juice, and 18 flavonoid standards. Red lines and blue lines mean the chromatogram at the wavelengths of 330 nm and 283 nm, respectively. Retention time and corresponding compounds are listed as: 3.13 min, eriocitrin; 3.41 min, narirutin; 3.51 min, naringin; 3.62 min, hesperidin; 3.70 min, neohesperidin; 3.78, diosmin; 4.23 min, didymin; 5.33 min, isosinensetin; 5.48 min, sinensetin; 5.63 min, 5,7,3′,4′-tetrathoxyflavone; 5.79 min, 5,6,7,4′-tetrathoxyflavone; 5.92 min, nobiletin; 6.06 min, 3,5,6,7,8,3′,4′-hetamethoxyflavone; 6.15 min, 5,7,4′-trimethoxyflavone; 6.29 min, 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone; 6.34 min, tangeretin. 6.46, Gardenin A; 6.71 min, Gardenin B.

Article Snippet: Eriocitrin, narirutin, naringin, hesperidin, neo-hesperidin, diosmin, didymin 3,5,6,7,8,3′,4′-heptamethoxyflavone, Tangeretin, 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone, Gardenin A, Gardenin B were purchased from ChromaDex (ChromaDex Inc, Santa Ana, CA, USA).

Techniques:

Journal: Plants

Article Title: Profiling of Flavonoid and Antioxidant Activity of Fruit Tissues from 27 Chinese Local Citrus Cultivars

doi: 10.3390/plants9020196

Figure Lengend Snippet: Biplot and Pearson correlation matrix for results obtained from peels ( A , D ), pulps ( B , E ), and juices ( C , F ) of 27 citrus cultivars. Different colored circle represented different citrus species ( A – C ). Figure inside letters are listed as: a-eriocitrin, b-narirutin, c-naringin, d-hesperidin, e-neohesperidin, f-diosmin, g-didymin, h-isosinensetin, i-sinensetin, j-5,7,3′,4′-tetramethoxyflavone, k-5,6,7,4′-tetramethoxyflavone, l-Nobiletin, m-3,5,6,7,8,3′,4′-heptamethoxyflavone, n-5,7,4′-trimethoxyflavone, o-5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone, p-Tangeretin, q-gardenin A, r-gardenin B, s-ABTS, t-DPPH, u-FRAP, v-TPC, and w-TFC ( D – F ).

Article Snippet: Eriocitrin, narirutin, naringin, hesperidin, neo-hesperidin, diosmin, didymin 3,5,6,7,8,3′,4′-heptamethoxyflavone, Tangeretin, 5-hydroxy-6,7,8,3′,4′-pentamethoxyflavone, Gardenin A, Gardenin B were purchased from ChromaDex (ChromaDex Inc, Santa Ana, CA, USA).

Techniques:

Journal: Antioxidants

Article Title: New Insights into the Metabolism of the Flavanones Eriocitrin and Hesperidin: A Comparative Human Pharmacokinetic Study

doi: 10.3390/antiox10030435

Figure Lengend Snippet: Phenolic compounds identified in the citrus extracts by HPLC-DAD-MS/MS.

Article Snippet: The flavanone standards eriocitrin, eriodictyol, homoeriodictyol, and narigenin were purchased from Extrasynthese (Genay, France).

Techniques:

Journal: Antioxidants

Article Title: New Insights into the Metabolism of the Flavanones Eriocitrin and Hesperidin: A Comparative Human Pharmacokinetic Study

doi: 10.3390/antiox10030435

Figure Lengend Snippet: Main metabolic transformations of hesperidin and eriocitrin to their corresponding phase-II conjugates. The identification and quantification of metabolites (M) can be found in and , respectively. The pharmacokinetic values can be found in . Black lines, microbial metabolism; blue lines, phase-II metabolism; red lines, phase-I or microbial metabolism; dashed lines, proposed new metabolic steps in the human metabolism of hesperidin and eriocitrin. The thickness of the lines represents the most favored pathways. LE, lemon extract; OE, orange extract (hesperidin); glur, glucuronic acid; sulf, sulfonic acid. The formation of eriodictyol ( M12 ) from hesperetin mainly occurs via 4′-demethylation of hesperetin ( M17 ) and the formation of naringenin ( M15 ), after 4′-demethylation plus 3′-dehydroxylation. Besides, M12 could also be formed after CYP-catalyzed 3′-hydroxylation of M15 . These steps were supported by the detection of eriodictyol and naringenin conjugates after hesperidin intake in plasma and urine. However, no homoeriodictyol or derived metabolites ( M16 , M6 , M10 ) were observed after hesperidin intake, which indicates that 4′-methylation to yield back hesperetin was favored instead of the subsequent 3′-methylation of eriodictyol to yield homoeriodictyol after consuming hesperidin .

Article Snippet: The flavanone standards eriocitrin, eriodictyol, homoeriodictyol, and narigenin were purchased from Extrasynthese (Genay, France).

Techniques: Clinical Proteomics, Derivative Assay, Methylation

Journal: Scientific Reports

Article Title: Expression and functional analysis of the nobiletin biosynthesis-related gene CitOMT in citrus fruit

doi: 10.1038/s41598-020-72277-z

Figure Lengend Snippet: Flavonoid accumulation in the flavedos of Satsuma mandarin and Ponkan mandarin during fruit maturation. The total flavonoid content is the sum of identified flavonoids (narirutin, naringin, hesperidin, poncirin, isorhoifolin, rhoifolin, sinensetin, nobiletin, tangeretin and heptamethoxyflavone). Total PMF content is the sum of sinensetin, nobiletin, tangeretin and heptamethoxyflavone. Columns and bars represent the means ± SE (n = 3), respectively. The significant difference between Satsuma mandarin and Ponkan mandarin is indicated by asterisks (* P < 0.05, ** P < 0.01).

Article Snippet: Standard flavonoids (eriocitrin, narirutin, naringin, hesperidin, rhoifolin, isorhoifolin, diosmin, sinensetin, nobiletin, tangeretin and heptamethoxyflavone) were purchased in FUJIFILM Wako Pure Chemical Corporation (Japan).

Techniques:

Journal: Plants

Article Title: Genome-Wide Association Study of Healthful Flavonoids among Diverse Mandarin Accessions

doi: 10.3390/plants11030317

Figure Lengend Snippet: Concentration range of 28 flavonoid compounds detected in peel, pulp, and seed samples from diverse mandarin accessions.

Article Snippet: Analytical-grade standard compounds apigenin, coumarin, didymin, diosmetin, diosmin, eriocitrin, eriodictyol, heptamethoxyflavone, hesperetin, hesperidin, isosakurenetin, isosinensetin, kaempferol, limonin, luteolin, naringenin, naringin, narirutin, neodiosmin, neoeriocitrin, neohesperidin, nobiletin, nomilin, poncirin, quercetin, rhoifolin, rutin, scopoletin, scutellarein, sinensetin, tangeretin, taxafolin, umbelliferone, and the internal standard catechin were purchased from Indofine Chemical (Hillsborough, NJ, USA).

Techniques: Concentration Assay

Journal: Plants

Article Title: Genome-Wide Association Study of Healthful Flavonoids among Diverse Mandarin Accessions

doi: 10.3390/plants11030317

Figure Lengend Snippet: The most significant GWAS-identified SNPs found for each compound in each sample type.

Article Snippet: Analytical-grade standard compounds apigenin, coumarin, didymin, diosmetin, diosmin, eriocitrin, eriodictyol, heptamethoxyflavone, hesperetin, hesperidin, isosakurenetin, isosinensetin, kaempferol, limonin, luteolin, naringenin, naringin, narirutin, neodiosmin, neoeriocitrin, neohesperidin, nobiletin, nomilin, poncirin, quercetin, rhoifolin, rutin, scopoletin, scutellarein, sinensetin, tangeretin, taxafolin, umbelliferone, and the internal standard catechin were purchased from Indofine Chemical (Hillsborough, NJ, USA).

Techniques: Marker