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Image Search Results
Journal: Radiation research
Article Title: Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation
doi: 10.1667/RR14514.1
Figure Lengend Snippet: Representative images of H&E-stained sections of the dorsal and ventral tongue, lip vermillion, mouth mucosa and neck skin obtained from mice at day 8 after five daily fraction of 6 Gy (cumulative dose of 30 Gy) and treated with vehicle control or entolimod (1 μg/mouse, 30 min before or 1 h after irradiation). Yellow arrows indicate mucosa and epidermal layers, green arrows indicate submucosa with hair follicles and sebaceous glands.
Article Snippet: A stock solution of
Techniques: Staining, Control, Irradiation
Journal: Radiation research
Article Title: Mitigation of Radiation-Induced Epithelial Damage by the TLR5 Agonist Entolimod in a Mouse Model of Fractionated Head and Neck Irradiation
doi: 10.1667/RR14514.1
Figure Lengend Snippet: Semiquantitative scoring of radiation-induced tissue damage. Injury scores were assigned to H&E-stained sections of the dorsal and ventral tongue, lip vermillion, mouth mucosa, upper esophagus and neck skin collected on the indicated days after delivery of the first irradiation (mean ± SEM, n = 4). Numbers above brackets connecting bars are P values indicating statistical significance of the difference in average morphology scores at a given time point between corresponding groups of irradiated mice with or without entolimod treatment (by Student’s t test). Where no P value is shown, the difference between groups irradiated with or without entolimod treatment was statistically nonsignificant (P > 0.05). *Statistically significant (P ≤ 0.05) difference in average morphology scores between groups injected with entolimod before and after irradiation (Student’s t test). #No change in morphology in the analyzed tissues (injury score 0).
Article Snippet: A stock solution of
Techniques: Staining, Irradiation, Injection
Journal: Medicinal Research Reviews
Article Title: Recent clinical trends in Toll‐like receptor targeting therapeutics
doi: 10.1002/med.21553
Figure Lengend Snippet: TLR5 targeting ligands in clinical trials
Article Snippet:
Techniques: Adjuvant