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Cayman Chemical
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EIDD 1931 is a ribonucleoside analog with antiviral activity It inhibits replication of severe acute respiratory syndrome coronavirus SARS CoV in Vero 76 cells Middle East respiratory syndrome coronavirus MERS CoV in Calu 3 2B4
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Image Search Results
Journal: bioRxiv
Article Title: Lassa virus NP DEDDh 3’-5’ exoribonuclease activity is required for optimal viral RNA replication
doi: 10.1101/2023.04.12.536665
Figure Lengend Snippet: (A). Vero cells were treated with 5’-FU and EIDD-1931 at indicated concentrations. At 48 hr post treatment, cell viability was measured using CellTiter-Glo Viability Assay (Promega). Data shown are the average (n=4) and SEM. (B) and (C). Vero cells were treated with 5-FU and EIDD-1931 at different concentrations as indicated. Cells were infected with wt rLASV (wt) and ExoN-rLASV (ExoN-) at MOI 0.1. At 48 hpi, virus titers were determined by plaque assay. Log10 virus titer changes relative to the virus titer of non-treated cells are shown. Data presented are the mean and the SEM of three independent experiments.
Article Snippet: Treatment of Vero cells with
Techniques: Viability Assay, Infection, Virus, Plaque Assay