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e)-sis3 ![]() E) Sis3, supplied by Solarbio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/e)-sis3/e++sis3/pmc09180362-68-5-8 Average 90 stars, based on 1 article reviews
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2026-09
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Journal: International Journal of Environmental Research and Public Health
Article Title: Inhibition of HIF-1α Attenuates Silica-Induced Pulmonary Fibrosis
doi: 10.3390/ijerph19116775
Figure Lengend Snippet: Cells were treated with DMSO, DMOG, SIS3, and SIS3 + DMOG in the presence or absence of TGF-β1 and changes in mRNA and protein were examined to infer the degree of transdifferentiation. ( A ) Western blot analysis of different groups COL1A1, HIF-1α, SMAD 3, and PSMAD3. β-actin was used as loading control. ( B ) Quantitative analysis of COL1A1, HIF-1α, P SMAD 3/ SMAD 3, and α-SMA is shown in A. ( C ) Different reagents were used to treat different groups of cells, and mRNA was extracted. mRNA expression was determined by qPCR and normalized to β-actin. * p < 0.05 vs. control group; # p < 0.05 vs. TGF-β1; % p < 0.05 vs. DMOG; & p < 0.05 vs. TGF-β1 + DMOG group Results are expressed as means ± SD. ANOVA was used to compare multiple groups and pairwise comparisons were compared by LSD-t test. A value of p < 0.05 was considered to be statistically significant.
Article Snippet: KC7F2 (IK0250, Solarbio, Beijing, China), (
Techniques: Western Blot, Expressing